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Database: UniProt
Entry: A0A1E3W2B6_9RHIZ
LinkDB: A0A1E3W2B6_9RHIZ
Original site: A0A1E3W2B6_9RHIZ 
ID   A0A1E3W2B6_9RHIZ        Unreviewed;       475 AA.
AC   A0A1E3W2B6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   16-JAN-2019, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AUC68_01750 {ECO:0000313|EMBL:ODR99879.1};
OS   Methyloceanibacter methanicus.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methyloceanibacter.
OX   NCBI_TaxID=1774968 {ECO:0000313|EMBL:ODR99879.1};
RN   [1] {ECO:0000313|EMBL:ODR99879.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R-67174 {ECO:0000313|EMBL:ODR99879.1};
RX   PubMed=27501305;
RA   Vekeman B., Kerckhof F.M., Cremers G., de Vos P., Vandamme P.,
RA   Boon N., Op den Camp H.J., Heylen K.;
RT   "New Methyloceanibacter diversity from North Sea sediments includes
RT   methanotroph containing solely the soluble methane monooxygenase.";
RL   Environ. Microbiol. 0:0-0(2016).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ODR99879.1}.
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DR   EMBL; LPWG01000010; ODR99879.1; -; Genomic_DNA.
DR   RefSeq; WP_069436715.1; NZ_LPWG01000010.1.
DR   EnsemblBacteria; ODR99879; ODR99879; AUC68_01750.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      167    388       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     175    182       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      452    472       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   475 AA;  53507 MW;  857A95AC5DE588F8 CRC64;
     MAHQDDPCAP GEAWTRVKSR LRGELGEDVY ASWFRGVEVD DIAGGVIHLT VATRFLRNWL
     RTHYYDTVLR QVQGEWPDAE RLEFSVRQPH FTAEPPKDVT IPRAASASVV AQRASLPMPL
     RTGYDGFEGS PLDPRLSFGS FVVGNTNKLA HAAAHQVALS SASPQSPFNP LFLHGNVGLG
     KTHLLHAIAW EVKRQKPEAE VLYLTAERFM SGFVQALRAR DALAFKEKLR NIDILLIDDM
     EFLQGPTIQQ EFCHTLNSLI DGGRQVVVAA DRAPTHLDKL DMRMRSRLGG GSSPEMKGMD
     YDLRHQILQK RALEACAETN GLEVSDTVLA FLAERLTESG RELEGAVHRL RASYQLTDEP
     VTIAVAEQIV RDLMRGAEPR RVRIDDILRT VSKHYGVNRS DLLSGRRNRS IVRPRQIGMY
     LAKLLTSRSL PEIGRRFGNR DHTTVLHAIR KIEQLMGDDT QLREEIELLK RLLRD
//
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