GenomeNet

Database: UniProt
Entry: A0A1E3XBA5_9BACT
LinkDB: A0A1E3XBA5_9BACT
Original site: A0A1E3XBA5_9BACT 
ID   A0A1E3XBA5_9BACT        Unreviewed;       452 AA.
AC   A0A1E3XBA5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   16-JAN-2019, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SCARUB_01994 {ECO:0000313|EMBL:ODS32888.1};
OS   Candidatus Scalindua rubra.
OC   Bacteria; Planctomycetes; Planctomycetia; Candidatus Brocadiales;
OC   Candidatus Brocadiaceae; Candidatus Scalindua.
OX   NCBI_TaxID=1872076 {ECO:0000313|EMBL:ODS32888.1};
RN   [1] {ECO:0000313|EMBL:ODS32888.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BSI-1 {ECO:0000313|EMBL:ODS32888.1};
RA   Speth D.R., Lagkouvardos I., Wang Y., Qian P.-Y., Dutilh B.E.,
RA   Jetten M.S.;
RT   "Draft genome of Scalindua rubra, obtained from a brine-seawater
RT   interface in the Red Sea, sheds light on salt adaptation in anammox
RT   bacteria.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ODS32888.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; MAYW01000045; ODS32888.1; -; Genomic_DNA.
DR   PATRIC; fig|1872076.5.peg.2348; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      144    275       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      356    425       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     152    159       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   452 AA;  52045 MW;  8B772A83C24DE53E CRC64;
     MSHLSKGEKQ TWLLIREKIR EKTTPQQFTT WFAGLCMIKF NVDEICVLAP NTYCKEWLED
     NYSDFISSVV NEVTNTNYKL KLIVKDRKNP ADYDPSTHYK LHPTDVEKRT YINKNYNFKN
     FLVGPCNRLA HAAALAVSDA PGTAYNPLFI HGPVGLGKTH LLHAILLHIQ KRSNQFNTLY
     LPCESFVNHY ISTIKSGDWD AFRKRYRQID VLLIDDIHFL SNSQSTREEF FHTFNALYSR
     RKQIVLSSDC PPEDIPTIED RLISRFKWGL MTRIDPPSFE TSVAIIQKKT ALLNINISYE
     AVRYLAVNAS SSIREIEGTL INIARHASLS PGKSKIDISL IKQVIKSFTR QKNYIGIEEI
     LNSVTKNFGV QLSQLHSKRK LKSIILPRQI AMYLARKLTN LSLEEIGGYM GGRDHTTVIH
     ADKKIRKLKK IDRNISITLR KIESELTKQH KH
//
DBGET integrated database retrieval system