ID A0A1E4J0D9_9BURK Unreviewed; 667 AA.
AC A0A1E4J0D9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetoacetate--CoA ligase {ECO:0000313|EMBL:ODU15887.1};
GN ORFNames=ABS94_15270 {ECO:0000313|EMBL:ODU15887.1};
OS Variovorax sp. SCN 67-85.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1660152 {ECO:0000313|EMBL:ODU15887.1, ECO:0000313|Proteomes:UP000094461};
RN [1] {ECO:0000313|EMBL:ODU15887.1, ECO:0000313|Proteomes:UP000094461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26031303; DOI=10.1111/1462-2920.12936;
RA Kantor R.S., van Zyl A.W., van Hille R.P., Thomas B.C., Harrison S.T.,
RA Banfield J.F.;
RT "Bioreactor microbial ecosystems for thiocyanate and cyanide degradation
RT unravelled with genome-resolved metagenomics.";
RL Environ. Microbiol. 17:4929-4941(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODU15887.1}.
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DR EMBL; MEFM01000020; ODU15887.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E4J0D9; -.
DR Proteomes; UP000094461; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ODU15887.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 27..83
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 92..482
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 549..624
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 667 AA; 73475 MW; 361511E26D0263F4 CRC64;
MSAPNIPQIR LYQNWLREKH GLSFDSYDAL WRWSTTELDA FWRSIWDYAA IQSPTPLASG
ATVLAERRMP GAQWFPGAQV NYAREVLRHV DAAHAAGMPA IVSDNERGDV REMSWPEMRR
QVASVALTLR ALGVRRGDRV AAYMPNVPET MVAFLACSSI GAVWSVCAPD MGTAAVADRF
RQIEPKVLIA VDGVHYGGKP LDRSAVLQEL RGQLPSVKKL VLVKSPFAAN AVPHDIDWSR
AIGRYDDEVN AFEPEWLPFD HPIWIVYSSG TTGLPKPIVH GQGGIILTMH ACGLHNDVGA
SYGANNLGER YHWYSSTGWV MWNSQLSGMA FGATICIYDG NPAGSKEKPD WSVLWRFVAR
HKVTFFGAGA AYFTNCMKAG LVARDCGDLS AVRALGSTGS PLPEEVQRWG SRQILDAGSS
EVWWCNISGG TDFCGAFVGG NRDLPEVPGQ MQCRELGHAV EAWNDDGQPV IGEVGELVCT
QPIPSMPLYF WGDEGNARYL SSYFDTYPGV WRHGDWIRIG TDGGCIIYGR SDATINRQGL
RMGTSEIYSA VEGLPEVLDS MVVDLEYLGR DSYMPLFVVL RPGVALDDGM RARLNNAIKT
SLSPRFVPND IFQVPEIPRT LSGKKQELPI KKLLLGQPLE KVVNREAMAN PGSLEWYVAF
AAERASA
//
