ID A0A1E4MDQ4_9SPHN Unreviewed; 762 AA.
AC A0A1E4MDQ4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:ODU69320.1};
GN ORFNames=ABT11_13065 {ECO:0000313|EMBL:ODU69320.1};
OS Novosphingobium sp. SCN 66-18.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1660121 {ECO:0000313|EMBL:ODU69320.1, ECO:0000313|Proteomes:UP000094170};
RN [1] {ECO:0000313|EMBL:ODU69320.1, ECO:0000313|Proteomes:UP000094170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26031303; DOI=10.1111/1462-2920.12936;
RA Kantor R.S., van Zyl A.W., van Hille R.P., Thomas B.C., Harrison S.T.,
RA Banfield J.F.;
RT "Bioreactor microbial ecosystems for thiocyanate and cyanide degradation
RT unravelled with genome-resolved metagenomics.";
RL Environ. Microbiol. 17:4929-4941(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODU69320.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MEGD01000024; ODU69320.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E4MDQ4; -.
DR Proteomes; UP000094170; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR007892; CHASE4.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF05228; CHASE4; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 362..495
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 504..752
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 762 AA; 85623 MW; D850A460AC360FD9 CRC64;
MGYLSRATAL RRTAGVLRSS WIVVATFLAL LALSVALVAS FSNSTRIADE LAQSDERVRV
AHYLDSSAKR ILAAQKLQQT WDDAMRHAVL GDDPVWTRTY LGYFFWGSQR ADHVFLVRAD
GSLVRGWERG EEAPADRYAG LQPRVARLIA RTHGESRDDG DIARWITLED GKWPVDRRGY
PMQRGLYEFS RYQGRPAIMT VAAIIPDSHV DLLQRAPNYV LLVRIMDETL LQELSRAVLL
DDMRVSDGPP SADRARNGTP IADPSGHTIG WLDWAARRPG EAIIRRTAPL LSAFILFFVG
VLLGGVMIVR RHMRTTRELV VSEAQAQHNA MHDAMSGLPN RVHYMQRLRQ ELSACINDQR
LGDVFVAYLD IDSFKVVNDT LGHHVGDELV RQVAMRLRRA LPSTDFLSRF GGDEFVLMRR
SPGGRATADE LGTQIMDLMR EPFLISGNTL EVTCSCGISW GPEQSEDPGE LLRRADIALY
RAKQRGRARY RRFTRDMDAS LKLRREMEME LRRAIARDEL SVAFQPIIGL PDGGIHGFEA
LLRWYHPDRG EIRPGLFVPV AEQAGLMIPL GNWVLRRVFN ECQGWPCDIS VNLSPLQIMA
SDFLVTLRTI LAETGMDPRR VVLEVTEGVM LDRSEHVFSV LRELNGMGFR IALDDFGIGY
SSLSYLRSFQ FDRIKIDRSF VQNVEGDVDA HSILCAIVSL GHTLRMKVVA EGVETDVQRQ
LVQAAGCELV QGHLFWAALA PQEAFALLTR DAEDGAKRRL VG
//
