ID   A0A1E4RC72_9ASCO        Unreviewed;      1628 AA.
AC   A0A1E4RC72;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN   ORFNames=HYPBUDRAFT_8293 {ECO:0000313|EMBL:ODV64823.1};
OS   Hyphopichia burtonii NRRL Y-1933.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Hyphopichia.
OX   NCBI_TaxID=984485 {ECO:0000313|EMBL:ODV64823.1, ECO:0000313|Proteomes:UP000095085};
RN   [1] {ECO:0000313|Proteomes:UP000095085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-1933 {ECO:0000313|Proteomes:UP000095085};
RG   DOE Joint Genome Institute;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA   Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA   Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA   Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA   Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA   Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA   Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KV454546; ODV64823.1; -; Genomic_DNA.
DR   RefSeq; XP_020073890.1; XM_020223725.1.
DR   STRING; 984485.A0A1E4RC72; -.
DR   GeneID; 30998274; -.
DR   OrthoDB; 20915at2759; -.
DR   Proteomes; UP000095085; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR018515; Tuberin-type_domain.
DR   InterPro; IPR027107; Tuberin/Ral-act_asu.
DR   InterPro; IPR024584; Tuberin_N.
DR   PANTHER; PTHR10063; TUBERIN; 1.
DR   PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR   Pfam; PF11864; DUF3384; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   Pfam; PF03542; Tuberin; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095085}.
FT   DOMAIN          1295..1532
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          1547..1572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1628 AA;  184957 MW;  75B25D6B0967258E CRC64;
     MSTHHPTFGR TSGIGNVFKS ITKSLKTSGS SSSSHPSNVS VRINPMVVGG STDQLLQHLR
     SGPLPARASA AAKMTETLES VSLSSFPEVW YAARDMCNPK IQSYIRRIAI TLLIQCIKQD
     ENSISDRLTF FKDITYFCQI SGSKVDDEFD LFIRALKNLT NDGKIIHDFC VYDQGKNLSQ
     FLLSALIALS NTQKKFNDSD SWRSDKNFRN LIELNNLIKN CFKFSFSILD ESSITSLISG
     ISELVYTTKN SIIMNSCLEV INTVVVFGAI PFKNFNQVMS LCCYTYGTLS NELLTKITWE
     IIHNLSIDAT FHLVLTSLCD VMTNPDLQVQ TSTNGHTNGT HTLSRSISSS ILSQSKRSMS
     SEQLVAKSST NNATAGLIDV RNPINTCIGA IQLMEKIQIE SALEDKPNFS CFLIPIFKAY
     KIALSFNIPL INTSILRSFD RLFSIDGTND VYSVNLTFEK LFPFHLWYSP TFSIYDVLDS
     LKLNSDLDIS YWKSICLSLQ GLFENHKLQT PKDKLVGLFF QHYNMLDSNN VNFILNFYHE
     ERLCTSVSPF AAENCNELLN CFYYGVNSNS EISHYDASIR IETLKIIKDS YILSMKLFNG
     FPKIEDIIYN IFRRSLNEKD PLVIRFLVND FLLDIGSRSS FSFFEKLLNI FFPLFQARSG
     NQDRLKSFIS IGSIGSGSQY SRTNGALAHN ETTINSERSI PDDNLFINED SNFRKSKIHP
     LMLVTVGESL VGLFVSCSNK YPRKSHLLYK AIIQMLQYSL STDNIELSLT MMRCLVRIRA
     TLEKYVYFIQ PTDMEGLATA LGRNTMASDF LNEDFKWIYP ESPDYLPEEF FNKPSKKLKL
     ADLKSINSYL NGTQYDESND ECTIEMSQWL RIVLDVMENV YHWELYTFIW AHFCSQLSNM
     ELFADYQELI VNLQQIICDQ LSLNLPKKLS IPKASVTITK ADLQVAYVRT LSGLLGYHEM
     FSKYEEDQII GSLIFGLGSW DKTAIPCIHI LTVCCYEIPI SIKKYLTAIL TKLQTRVTSL
     RASAHTLEFL VSLIHLPTLT SNFTTDEFKR VFAIAFKYIQ YSNDLRLRTQ YEPQSQPSIA
     HQQYGAETKV DNMVSTQLGE NSPMMNQYLL QLSYSAILAW FLKIDMNERR QVSGYLVKNL
     ILSNSDEKEL DDHTIAFLDL IIRFTYSNLP VKNIIPSKIS NTSLLSTENN ISTNRWILGN
     SIIGIDTNIL NGDSVLTIRR PTGVSILKLS LDPSMIPEWT EINDGNKLSK NFRGDRNKAL
     INSNYLLLQL FNNVDKGNNS KPIPIIEDAA TLRAISSLDR IPIVEFHKVG IMYIAPGQSS
     EVEVLGNDVG SRNYQNFIEG IGRIIKLKNC KDAYVGGLDT ENNLDGEHAI FWSDEVTHLI
     FHTTSMMPNN PNDKYFDLKK RHIGNNYVNI YFDESGLPFN FNLIKSQFNF LNVVISPHTI
     TSEFLLSEKP NNKEKFFKVK TYRREGVPGV FSTCHFKLIL ESQLAIFIRN LVLILDDFAN
     VWHSSGQSSY VSNWSHRVKQ IRLLKDKTLK NHQVLEEEQQ QQQLQQLTQA ASNHHHHPSS
     LSSAIGGDAK SNPTKDATFS FMEQLQYENT QSSPATTNLA SGESTGKYEY VSNNENELYT
     LLEFNSYT
//