ID A0A1E4RPS8_9ASCO Unreviewed; 558 AA.
AC A0A1E4RPS8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Proline specific permease {ECO:0000313|EMBL:ODV69280.1};
GN ORFNames=HYPBUDRAFT_151116 {ECO:0000313|EMBL:ODV69280.1};
OS Hyphopichia burtonii NRRL Y-1933.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Hyphopichia.
OX NCBI_TaxID=984485 {ECO:0000313|EMBL:ODV69280.1, ECO:0000313|Proteomes:UP000095085};
RN [1] {ECO:0000313|Proteomes:UP000095085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-1933 {ECO:0000313|Proteomes:UP000095085};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. YAT (TC 2.A.3.10) family. {ECO:0000256|ARBA:ARBA00006983}.
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DR EMBL; KV454538; ODV69280.1; -; Genomic_DNA.
DR RefSeq; XP_020078347.1; XM_020220336.1.
DR AlphaFoldDB; A0A1E4RPS8; -.
DR STRING; 984485.A0A1E4RPS8; -.
DR GeneID; 30994886; -.
DR OrthoDB; 1406943at2759; -.
DR Proteomes; UP000095085; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:UniProt.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43341; AMINO ACID PERMEASE; 1.
DR PANTHER; PTHR43341:SF36; PROLINE-SPECIFIC PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095085};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..509
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 558 AA; 61326 MW; 496EF1C59BD80754 CRC64;
MKDNKDFYSF NVSEGADDSI SVANSRIVSF DEKTGEKIEN ESEEKLHRGM KSRHLALISL
SGAIGTGLFV GSGASLAATG PGPLLLGYIF LSGIVYFVMN ILAEMSCFLS TSKSGSGAGA
FINDYLHPDL GFAFGYNYVY AFAILSASEV SILPALFDYF SDVHPAVWIT IFLVLLIALN
MAPVKFYGES EFWFGSIKLI TLTGLIILGI VLFFGGGPTH DRLGFRYWKN GNAFHQHLVK
GDTGRFLSVW TSIIKAGYSF ICSPELIVAG ASEVERPRRN IKKAANSFIY RLAFFYIFGS
LIIGIIADSR SPELLNTSGN ASASPFVLGI QNAGIPVLNQ IINAVVLTSA ASAGSSFLYA
ASRSLFSLSK RGLAPKIFAK TNRYQVPYVA VLANSCVTCL AYLNVSSTSA QVFTWLSNIS
TISGFIAWVG VAFAYIRWRK AIVVHNLSDR VPLRTPLQPY GAYIVIVFIS LLTLTNGYAV
FFDFNVADFF AAYVTFIFVF VLYLGRRLYS YFIKGEKRWL TPLEEVSFEG LDEFEAEDAS
YPEVVPRNLA EKAWLIIV
//
