ID   A0A1E4RRY5_9ASCO        Unreviewed;      1238 AA.
AC   A0A1E4RRY5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=HYPBUDRAFT_117947 {ECO:0000313|EMBL:ODV70049.1};
OS   Hyphopichia burtonii NRRL Y-1933.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Hyphopichia.
OX   NCBI_TaxID=984485 {ECO:0000313|EMBL:ODV70049.1, ECO:0000313|Proteomes:UP000095085};
RN   [1] {ECO:0000313|Proteomes:UP000095085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-1933 {ECO:0000313|Proteomes:UP000095085};
RG   DOE Joint Genome Institute;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA   Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA   Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA   Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA   Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA   Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA   Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   EMBL; KV454538; ODV70049.1; -; Genomic_DNA.
DR   RefSeq; XP_020079116.1; XM_020219189.1.
DR   AlphaFoldDB; A0A1E4RRY5; -.
DR   STRING; 984485.A0A1E4RRY5; -.
DR   GeneID; 30993739; -.
DR   OrthoDB; 2721902at2759; -.
DR   Proteomes; UP000095085; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0051170; P:import into nucleus; IEA:UniProt.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR045478; Exportin-5_C.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR045065; XPO1/5.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF3; EXPORTIN-5; 1.
DR   Pfam; PF19273; Exportin-5; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000095085}.
FT   DOMAIN          31..119
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   1238 AA;  141857 MW;  7CBE2934BA3FDDE5 CRC64;
     MTMDSNGVSQ IINALEVVYA PSSTNIQRRE AQSFLETIKS NEESPFWGYQ LSLPENNGKN
     FIVRHFGLSL LQNSINKKFH TFDQTKSLTI RKWVVDLCSK VDEADPHYIK EKLALLFVSI
     AKRIWGNYLV KSLTSDSKNN DDTVNDDDSL SGWTSLDCDL WNFWNSTMTS RELSLIIIRT
     LFEDIYLLDD PIASKRTALL NQLSVLIVTP DNVLNQLYEP NPKLSLCKFS TDGWFVNWSK
     FLIEILSNND FKSSTCQIFV PKILSTFKTC LHWIQPSLLK DENILSTLIN ILTIPDVKLK
     TLAVDCLHIL FTRSYNNEDD FEFFIGNIYT TEGITKLSQF YQSLEIDPED VDEQVYSLLK
     KTVEMIVSLS EYLNVSLPSK NKISWETADV ESYLNLVLST TGHPSLIISG LSLQMWVTIL
     RFDELSSKPI IQKILLNLLE IAANRTINYS NVDDENISKK FLEVDFDSTP DANSFLSNYR
     KFNEDIVRIT ICKKPEDGLM WLENRLQNFF SSPLGEQCIN SYKLDEKSDA LNYGNSQFNI
     IENSIRGISR WRIWYTGDDF DLINDRLNKL VESLGERLLA MRLSCPLLIR KQVQTLVQFA
     PLLKDVSPLM FQVLEKILTT ATFEYPANIS DEEKELIRDL RTSCGTELNR LAYIMPESLK
     KIFKDLENVV ANILSSNKVS DHENVAFKSF LLVIASRSSI DDKDELFASI VDPELLAWSA
     PETEKGLMDL HWFMERMGIV EIASYFQSRN ITGSTNLLEA KMDEEGKILK NRLKDHWSSI
     FPIRATRIFI QYSIEKLSHD SSEYLNLLKL WKPRVQPIIP HILQLLSQIQ AYHNPENWKD
     LPDAVQSFVR YSCMERFWQQ GVSIQSKETF IEENVKAALT LRDFADSVGH LIRYTREYAF
     LTIGSLSQLE DTLYEIPGIA QMLWKSVAGD TSGVTLHSWK HMINSCLRSI VRNCPVKFVD
     IFMAELLPKA FVDIDQLIVG RWEKVYVNGL QLQGNEDDET LSEEMMEEHM LRQLTATVVR
     LLMDVVSQIN AKNVTDTQFA CKRLIIENKE VMAPFLQICC HIISFKDTKC SFNTILVVRN
     ILSDILLKDD EVDKYLCDNL IKSLLHVLTD DYFVETHSEA AIALTTLYCT LRSKNDYPAR
     VLIQYLPNIT TQHVSNFETL LVSSKSLKHQ RSALLELIKI SKENLNGGGA SADSELKDRK
     KQLEAAAIAR KKKNAAIDIM NDPYTENGAL NNLFGDES
//