ID A0A1E4RUC3_CYBJN Unreviewed; 348 AA.
AC A0A1E4RUC3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Dihydrokaempferol 4-reductase {ECO:0000313|EMBL:ODV70873.1};
GN ORFNames=CYBJADRAFT_178824 {ECO:0000313|EMBL:ODV70873.1};
OS Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617
OS / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Cyberlindnera.
OX NCBI_TaxID=983966 {ECO:0000313|EMBL:ODV70873.1, ECO:0000313|Proteomes:UP000094389};
RN [1] {ECO:0000313|EMBL:ODV70873.1, ECO:0000313|Proteomes:UP000094389}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 /
RC NRRL Y-1542 {ECO:0000313|Proteomes:UP000094389};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; KV453948; ODV70873.1; -; Genomic_DNA.
DR RefSeq; XP_020067912.1; XM_020216959.1.
DR AlphaFoldDB; A0A1E4RUC3; -.
DR STRING; 983966.A0A1E4RUC3; -.
DR GeneID; 30991355; -.
DR OMA; VADENSW; -.
DR OrthoDB; 1200131at2759; -.
DR Proteomes; UP000094389; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05227; AR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000094389}.
FT DOMAIN 7..260
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 348 AA; 38293 MW; 43FCCAD4704D6E8B CRC64;
MAAKALLVSG ASGFVALHIV GELLSEGFEV VGTVRSQAQA DKLLARFKAK YPHGSLTYSI
VPDISKDCAF DKVFETVDDI DYVLHTASPF SFGLEGTLED IYLIPAVNGT LNMLKSVHKL
APQVSKVVVT SSMASIQNFD KVGDASFIHT ESTWNPIQWD EVTDENMAYV ASKKLAEKAA
WDFVKDNDVK FKLNTVTPPY IFGPQYFEED ASLDKINTSS GLIAALLKSD PKDTHLFSEP
SLCAVDVRDV AKAHCFALRP EISNERLFVA SERFTLQGIL DIINKDFPEL DGKIAKGQPE
GEKSIPTSYF DNSKTKEIMG GYEFVPLETS VFDTVKQLLE QGNLKSTL
//
