ID A0A1E4RWM5_CYBJN Unreviewed; 1315 AA.
AC A0A1E4RWM5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=TORC1 growth control complex subunit Kog1 {ECO:0000313|EMBL:ODV71664.1};
GN ORFNames=CYBJADRAFT_178498 {ECO:0000313|EMBL:ODV71664.1};
OS Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617
OS / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Cyberlindnera.
OX NCBI_TaxID=983966 {ECO:0000313|EMBL:ODV71664.1, ECO:0000313|Proteomes:UP000094389};
RN [1] {ECO:0000313|EMBL:ODV71664.1, ECO:0000313|Proteomes:UP000094389}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 /
RC NRRL Y-1542 {ECO:0000313|Proteomes:UP000094389};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC {ECO:0000256|ARBA:ARBA00009257}.
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DR EMBL; KV453939; ODV71664.1; -; Genomic_DNA.
DR RefSeq; XP_020068703.1; XM_020216934.1.
DR STRING; 983966.A0A1E4RWM5; -.
DR GeneID; 30991330; -.
DR OMA; HHHPLWK; -.
DR OrthoDB; 103066at2759; -.
DR Proteomes; UP000094389; Unassembled WGS sequence.
DR GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR004083; Raptor.
DR InterPro; IPR029347; Raptor_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR Pfam; PF14538; Raptor_N; 1.
DR Pfam; PF00400; WD40; 1.
DR PRINTS; PR01547; YEAST176DUF.
DR SMART; SM01302; Raptor_N; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000094389};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 53..207
FT /note="Raptor N-terminal CASPase-like"
FT /evidence="ECO:0000259|SMART:SM01302"
FT REPEAT 1203..1225
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 409..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1315 AA; 149589 MW; 6C8064C4E0386C28 CRC64;
MDQQYMEFLA NNFFLYFDDK RHHTAGNALT DDEKAANRDY YQPIADWKVM KDRQKTVSAA
IVLCLNIGVD PPDVVKTHPC AKTEAWIDPV TFNDTKKAIE AIGKNLQSQY ETLSLKTRYK
QSLDPCVEDV KRFCNSLRRN ARDERILFHY NGHGVPQPTQ SGEIWVFNRN YTQYIPISLY
DLQTWLGAPC IFVWDCNSAG NIVTNFNKFV QKRIDDDNEV NHDQQSPSPA TAYIDCIQLA
ACRSNELLPM DPELPADLFT SCLTCPIDIS IKWFIMQSPI KRSYFGPLLE MAKNNPNGNI
IIPGKLTDRR TPLGELNWIF TAITDTIAWT SLPRPLFKRL FRQDLMVAAL FRNFLLATRI
MPTYGCHPIS DPPLPDTQFH SMWESWDLAI DQVLTQILKN VNESSSPLGQ VIQSPMVSPP
TTNGSSFSNS HSNQSSNGTS NFTNDQNLQN YQHSTFFEQQ LTAFELWLKF GSSARQPPEQ
LPIVLQVLLS QVHRVRALVL LSQFLDLGPW AVYLALSIGI FPYVLKLLQS PAPDLKPVLV
FIWARIMAVD YKNTQQELIK DKGFNYFLQM LNPKDPTNNI NNDHKALCAL ILSLFVKGFK
NGQKLCFSPD LVDRLLQYVE TSDNPLLRQW CALLISQLWE GNHEAKWICQ KEGLLDRLYK
QVNDPIPEVR ASVILALMAF LPDQEEDEEM KEETNVIMTV LSLANDASPV VRKEIVICLS
KIVKRHINNF IVLAFNELQI EISTVTNISI ENKQSIGYGS IYHIIFKALM LFSCDGYTQV
QIYAENIIDY ILIKLRESDL GDVVSEMEDL MIQSSASSTV VSSITQPLPK PFKINGTQQR
SVTVGDKDNK AQENSTSGFS LLRRTLSLSN ILRPFGWSSN NDSSNSADPS KSSMSNVFFN
DDSTLHPRTA RFDAKESQNE ELTLPLISNF FEYSVEYFQE PQMHKHEVDE PGSLEYTRRI
WRRNRNEGII NETQPQKNLS LRGDWKTNIA VLNNKTQPKL IKFAQFENYV VTSDDRDQVT
TFDWEESKQL SRFNNGNPFG TKITDLKLIN EDDLPLLFTG SSDGIVKLYK DFHSNTDVSL
VTSWRALTDL LLTPRSTGLL MEWQQSRGSL LATGDVKIIR IWDAPREMCL VDIPARSSSA
ITSLTSDQVA GNIFVAGFGD GSIRVYDRRV DPRDSMVKLW RNALGERSWI TNIHMQRGGY
RELVSGSTNS TINLWDIRMD EPVLTFKGHE KSMTSIQVHE HAPVIATGSR MVRIWTTSGD
LVSSFKNSSG FSSSLNNRTP FLSSLALHPH RMMLAANNQH DPYINIYKCT ETHQE
//
