ID A0A1E4RXG3_CYBJN Unreviewed; 742 AA.
AC A0A1E4RXG3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Zn-dependent exopeptidase {ECO:0000313|EMBL:ODV71963.1};
GN ORFNames=CYBJADRAFT_186221 {ECO:0000313|EMBL:ODV71963.1};
OS Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617
OS / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Cyberlindnera.
OX NCBI_TaxID=983966 {ECO:0000313|EMBL:ODV71963.1, ECO:0000313|Proteomes:UP000094389};
RN [1] {ECO:0000313|EMBL:ODV71963.1, ECO:0000313|Proteomes:UP000094389}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 /
RC NRRL Y-1542 {ECO:0000313|Proteomes:UP000094389};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; KV453937; ODV71963.1; -; Genomic_DNA.
DR RefSeq; XP_020069002.1; XM_020217205.1.
DR AlphaFoldDB; A0A1E4RXG3; -.
DR STRING; 983966.A0A1E4RXG3; -.
DR GeneID; 30991601; -.
DR OMA; NVVIASW; -.
DR OrthoDB; 67337at2759; -.
DR Proteomes; UP000094389; Unassembled WGS sequence.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000094389};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..742
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009162503"
FT DOMAIN 159..228
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 336..524
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 620..741
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 219..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 81640 MW; EC93426885937864 CRC64;
MGVSDKSASS GGVTTSLVKL LCIASSVLAL PTYDETSEKL SIDEITKIYQ DVLTSSNNAG
DWLKTYTQEQ HLAGQNYHLA EFTAQRFEEF GFKAKFENFS VYINYPVENS IKVLEPNEDG
SYELTYQPTL VEDELEEDPT TSGEGLVPAF HGYSANGNVT AELVFANYGT KEDFALLAEN
NIDLEGKIVI VRYGGIFRGL KVKFAQEAGA LGVITYSDPA DDYSPPDAEP YPKGPGRNPS
SIQRGSVQFL SSLPGDPSRF TDRSPEALSN LTTIPRIPSL PISYKEAIPI LETLNGYGSD
LGFKGGVSTF NYTTGPSSAK INLYNNVEYD FTNITNVYGL IEGQEADKVV IIGNHRDAWV
KGGAGDPNSG SAVLLELARG LNELFKQGYK PRYSILLASW DGEEYALLGS TSYAEKYAAK
LDKQAVGYIN VDVAVGGTHL ELAGSPLFNQ LLLDQGSLVT HPDTNVSLTE RFLNESEILI
LGSGSDYTTF YEHLGIPSID LGFNPGLGDP VYHYHSNYDS YHWISTFADP GFKYHNALAQ
YLGLLTLKLT EEKLLKSYST SDYASAVAGY FSTLVSTIPQ DWLNQTVVLD DDIIAPYSYS
EDNLTSTDVT VLRDLITATN DTLSILEEVA KHHDEEKEYL QSQWDESVST SSSPITKTLF
DKRVATINDK SRNFEKQFLY EGGLKSREWF KHIVYASGRY TGYAGQSLPG LTEALEDDSF
DEAARWIHIL QVAAQRAIAS LV
//
