ID A0A1E4RXZ4_CYBJN Unreviewed; 1037 AA.
AC A0A1E4RXZ4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 08-NOV-2023, entry version 33.
DE SubName: Full=p-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:ODV72100.1};
GN ORFNames=CYBJADRAFT_168789 {ECO:0000313|EMBL:ODV72100.1};
OS Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617
OS / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Cyberlindnera.
OX NCBI_TaxID=983966 {ECO:0000313|EMBL:ODV72100.1, ECO:0000313|Proteomes:UP000094389};
RN [1] {ECO:0000313|EMBL:ODV72100.1, ECO:0000313|Proteomes:UP000094389}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 /
RC NRRL Y-1542 {ECO:0000313|Proteomes:UP000094389};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
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DR EMBL; KV453936; ODV72100.1; -; Genomic_DNA.
DR RefSeq; XP_020069139.1; XM_020215504.1.
DR AlphaFoldDB; A0A1E4RXZ4; -.
DR STRING; 983966.A0A1E4RXZ4; -.
DR GeneID; 30989900; -.
DR OMA; FARCDIQ; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000094389; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000313|EMBL:ODV72100.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000094389}.
FT DOMAIN 16..264
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 734..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1037 AA; 116325 MW; 34D8C53CA089BBEB CRC64;
MRVTPDTLLR LQKDPQSIRN ICIVAHVDHG KTSLSDSLLA SNGIISQRLA GKVRYLDSRP
DEQLRGITME SSAISLYFRV LHKKGDGEEG YDAKEHLINL IDSPGHIDFS SEVSTASRLC
DGAVVLVDVV EGVCSQTVTV LRQCWIDKLK PILVLNKIDR LITELRLTPS EACLHLTKVV
EQVNSVIGSF FSGERMAQDL AWREQLEKEG HSGKEFVEED DKDIYFDPAQ NNVIFSSAID
GWGFNISQMA RFYENKLGIK RENLQKVLWG DFYLDPKTKK IIGPKGLKGR SLKPLFQQLV
LENIWKIYEN IVIEKNAEVL EKIVKALNIK VLPRDLRSKD NKALLSQVMG QWLPVSSAVL
LTVTEKLPSP LESQRTRIPT VLESAPHHEL IDPGLREAML SCDNNGPVSA YVSKILSVPE
DELPRNSRAK LSEDELAERS KRARELAAKA AEQAKILEGD QEDQIVDEFA QVKVSNNDPY
SLFEYEEEEE EEEIEVKKEE LIGFARVYSG TLRIGQELSV LEPKYDPANP KEHIQTATIT
ELYLLMGKEL VPLDEVPSGN IAGIGGLAGK ILKNGTLIEP GIIGVNLAGV SLSVPPIVRV
AVEPVNPTQM DKLERGLELL NQADPCVQTF LEDTGEHILA TAGELHLERC LKDLKERFAG
IEITASEPVI PYRETFIETL DLNPPKNPDL GRGVAEFELG NVHIKMRAVP LPQPVIDFLL
ENHATIKKLV DSINKRRSED EEEEDGLNDL EDDAVGSSSI TDATTFKKKL QALFDADEKH
RDIWSGIVDR ISVFGPKRTG PNILFDTSKE SIRRVFSQSD ETRFRFENSI VNGFQLSTQN
GPLAHEPVQG MAIIMEDIRE VDEADQEDST PVPNLLGRLI TTTRDNIHQA LLDWSPRIML
AMYTCDIQAS AEVLGKVYAV VQQKRGHIVS EEMKEGTPFF QIIAKLPVVE AFGFSEDIRK
RTSGAAQPQL VFSGFESIDE DPFWVPTTEE EMEALGEFAE RENIARKYMN QIRKRKGLFV
DEKVVQNAEK QRTLKRN
//
