ID   A0A1E4SPT7_9ASCO        Unreviewed;       771 AA.
AC   A0A1E4SPT7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Ubiquitin ligase of SCF {ECO:0000313|EMBL:ODV81533.1};
GN   ORFNames=CANTADRAFT_87517 {ECO:0000313|EMBL:ODV81533.1};
OS   Suhomyces tanzawaensis NRRL Y-17324.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Suhomyces.
OX   NCBI_TaxID=984487 {ECO:0000313|EMBL:ODV81533.1, ECO:0000313|Proteomes:UP000094285};
RN   [1] {ECO:0000313|Proteomes:UP000094285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-17324 {ECO:0000313|Proteomes:UP000094285};
RG   DOE Joint Genome Institute;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA   Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA   Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA   Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA   Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA   Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA   Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KV453909; ODV81533.1; -; Genomic_DNA.
DR   RefSeq; XP_020066655.1; XM_020211349.1.
DR   AlphaFoldDB; A0A1E4SPT7; -.
DR   STRING; 984487.A0A1E4SPT7; -.
DR   GeneID; 30985485; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000094285; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000313|EMBL:ODV81533.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094285};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          419..645
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   771 AA;  89968 MW;  349D2C1CE44D0D16 CRC64;
     MSLPIANDLD ATWNFIQPGL EYILGSHEDQ GVTSKMYMNC YTAVYNFCVN KSRRSNNDHH
     STANESNLYS LAGAEIYSRL DKYLTEFIRN LKKDPKDTFL EFYVRKWTRF TIGAGYLHNV
     FDYMNRYWVQ KERSDGRKDI HEVNTLALNK WKTEMFNDNA EVLISEILDL IEKQRNNQIV
     NTQLISIAIK SLVFLGLETQ DSKKPSLVVY ITNFEKAFLE KTSQYYSNES AKFLSENNVV
     EYMKKCESRL SEEISRSNNY LEDHTKKYLL ETLNKVLIED HSQEMYNQFL TLLEQNEIDH
     IQRMYKLLYK VPKTIDPLAD TLENYIKQQA LLSIEDMRIS MEAAQDNSTT TASKPKRALS
     AVDPKTYINT LITIYLQFNE IVIKAFNKDP RFIKALDNAC RYFVNNNPIA LPTPKSACKT
     PELLAKYSDL FLRSNSKESD IIDMNGDNLM IIFKFINDKD SFEEFYRRQL AKRLINSNSK
     SEELEESIIQ RLQEENSIEY TSKMTKMFSD MKASEDLKSK LNMNNLIVKD FNPLILAQSM
     WPFNHSKDYN LNVASELIEP FDNIVKAYDS QHNGRQLKWL WNHGRAEVKA NLSKKGKPPF
     LFTVSNIQLM ILIAFNKNNT YTLGNLYEIV GTSRHIFESH LLPLIKYKLI EQSPAGDLSN
     DDITLTIVEE YKSKKLKVNF ISVIKNTEPK QEEEEATKEI DETRKNFLSA CIVRIMKSRK
     VVKHNDLINE VLPQTLSRFR AKIIDVKRVI DQLIEKQYIQ RVEGNSYEYL S
//