ID A0A1E4TJ14_9ASCO Unreviewed; 990 AA.
AC A0A1E4TJ14;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=CANCADRAFT_30072 {ECO:0000313|EMBL:ODV91736.1};
OS Tortispora caseinolytica NRRL Y-17796.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Trigonopsidaceae; Tortispora.
OX NCBI_TaxID=767744 {ECO:0000313|EMBL:ODV91736.1, ECO:0000313|Proteomes:UP000095023};
RN [1] {ECO:0000313|Proteomes:UP000095023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-17796 {ECO:0000313|Proteomes:UP000095023};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Jeffries T.W., Grigoriev I.V.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KV453841; ODV91736.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E4TJ14; -.
DR OrthoDB; 1330350at2759; -.
DR Proteomes; UP000095023; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 2.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 2.
DR Pfam; PF13516; LRR_6; 2.
DR SMART; SM00100; cNMP; 2.
DR SMART; SM00367; LRR_CC; 8.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF52047; RNI-like; 2.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Reference proteome {ECO:0000313|Proteomes:UP000095023};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 88..205
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 273..374
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 990 AA; 108278 MW; 11E65C8F874C0A9B CRC64;
MRSDSGRRGP RKSHTRGYSN ASSTYDRHSI SINSNAYYRP TDPGSGVVKP RRSSSDPKLY
APIRPSPLST ASNGMPLEIF ERISEFPLFK SAPESFLLEV AGKLRPHQAG PGDSIIIEGT
EAKAMYWIVR GSVSVSSRDG ESIYSTLQPG SFFGEIGILF NCPRTATVSA QSRCLLVVLT
AEALHSILPS YPDVEKSLRN EAEVRLVLTQ KFKDRKKGRL SSDISSSSLT DSNDGHSQTA
MANVSSFTDS EIPGKPIFLH VSQVTSRLKE SPLFSHLPDD ALHSLALAVE PRRFGPFEVI
LQEGTRGQAI YFITDGEVEV IRQGLLKALS RLGPNTYVGE IGFLDMSRTR TATVRTISDV
QCLCLSRNAL NNVLDKYPAL QAQIQETAQT RLQALVSENN SQALEGVSPQ EMLMSGESAS
SPSDYSLSVL PEHEELSPTA MPADPVSMPE SQIPEADLGP TDTCTVTIKR PFTVVEPASI
PLDPDPYSNV AGANDAQDMT KARTPGRRSS LAPKTDDNEQ GSSNTDKTEE RDIMMVDNSD
VSTIDTQSSE SVPLVYNPAF SMTGDTKQEE QSFFYERSGS VFSVLDNGVP KRPRLVNSFS
SMTKDIDMYS SQPLINSNLS VLGKILSYLP LLEKIRKQRV CRTWKKVLLS APEVGEVLDL
SPYNTVIYDT IIPHIVAFMN GRKPRYIDLS NCFHLSDAGF RMLACNCIGP ATLVLKMKSV
WDISGSAITE IAAKARGLAI EELDFSNCRK IGDSSLARII GWNYPGLLAG LEGKKGQDRI
ELLEQLAAES EEAGIGFLGC TSLRRLTLSY CKHISDRSMH HISLHASHRL EHLDLTRCTT
ITDHGFGYWA MKPFPNLRSI CLSDCTFLTD NAIVSLAGAA KNLEYLNLNF CCALSDVAVE
VLALGCTNLK SLNLSFCGSA VSDSSLKTVA LHLLNLEYLS VRGCVRVTGI GVDTILGGCV
MLKKFNVSQC RNLSTYNKGL AKRQGVEMIF
//
