ID A0A1E4TQR4_PACTA Unreviewed; 793 AA.
AC A0A1E4TQR4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=PACTADRAFT_81695 {ECO:0000313|EMBL:ODV94090.1};
OS Pachysolen tannophilus NRRL Y-2460.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Pachysolen.
OX NCBI_TaxID=669874 {ECO:0000313|EMBL:ODV94090.1, ECO:0000313|Proteomes:UP000094236};
RN [1] {ECO:0000313|Proteomes:UP000094236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2460 {ECO:0000313|Proteomes:UP000094236};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KV454016; ODV94090.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E4TQR4; -.
DR STRING; 669874.A0A1E4TQR4; -.
DR OrthoDB; 2056550at2759; -.
DR Proteomes; UP000094236; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF4; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5; 1.
DR Pfam; PF02735; Ku; 1.
DR SMART; SM00559; Ku78; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000094236};
KW Telomere {ECO:0000256|ARBA:ARBA00022895}.
FT DOMAIN 367..517
FT /note="Ku"
FT /evidence="ECO:0000259|SMART:SM00559"
FT REGION 333..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..525
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..777
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 793 AA; 90879 MW; FBB3C3E0B4525DA3 CRC64;
MADKEFTFFI IDLSPAMGEL NNGRSLSDLD YILEYLFDVV STKIIMGKKQ DQICVIASHS
VGTNNPLATE LENRNISILL PVKHANFEDL KKLKNQLVVN PAEIDEEVEG DLIKSLLVAF
SMTEDRKLNK NAFTKINFMI LTNNKSKINF LQDYQLAIPE ILKSFNNAKL YLVSVDHGLY
DNDLNSLKKL NEKNWENLFK FFNNDSSIIT GGEAIAQIEV LKNAVPRIYK PTKTFDGELR
IGCDLNEIDN NNFEFLNSFG KDDDDDKNNS FKYDQYRDIV SICIAVEGYP FIKKEQGMSA
KNYAYYPNER DLSKAGELHS LKYITDYYIH KKSQSEEPDG EKTEDKEQTR VMKDEEEEED
EEEEEDVEFV RLSEIMRAYK YGKSTIPLTK NLEKILKFRT FPGIDIRGII RISDLPPWYL
TGESILVVNK GSQTLSSNNS NASVRDVLAF NSLCQSLINL ESIFIVRYVL KKDSEVNMGA
LIPVLVNSDK ATDKAKVKAH TSSQSPKNLQ KMVKEEEDEE DNLKESLKRN FSTQQAQENS
EDKIYAFSLV RLPFREDEKF PNYNRLTGLI KSDDSNANAN EKFSKILPSE EMLETMNKFV
ESMDLDKDKG QDTEIETNYL TANEYDHSLP LPNKHHERNL SSGNLSKISS DFLFYPSPSI
HVLSKVLKKI VLTLLPQEDI NELEIGDNQE VPTRLQKLIL TNQQVVDKII DEYAQNFKSK
INIEVSNPSN YHNLDTELIS NMQRIFDNAY MNDAELQKNK GAGTKTGRDE LRVRGDANDQ
YESFDIDKIL ERG
//
