ID A0A1E4TY84_PACTA Unreviewed; 1498 AA.
AC A0A1E4TY84;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PACTADRAFT_48513 {ECO:0000313|EMBL:ODV96691.1};
OS Pachysolen tannophilus NRRL Y-2460.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Pachysolen.
OX NCBI_TaxID=669874 {ECO:0000313|EMBL:ODV96691.1, ECO:0000313|Proteomes:UP000094236};
RN [1] {ECO:0000313|Proteomes:UP000094236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2460 {ECO:0000313|Proteomes:UP000094236};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV454012; ODV96691.1; -; Genomic_DNA.
DR STRING; 669874.A0A1E4TY84; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000094236; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:UniProt.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000094236}.
FT DOMAIN 46..241
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 674..850
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 1139..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1139..1158
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1498 AA; 171347 MW; E76D6456321B85C8 CRC64;
MFLRVDQNKG LFYFDATYRP CPLSQQFVGI NEKRALKRYQ ANNEVCYEKI LESVSEGNQV
IVFVHSRKDT FKTAKWIRDK LLENNQLNKL LKSDSGSIEI LKQESENCKD SGLKDLLPTG
FALHHAGLNR SDRSLSEDLF AAGYIQVLVS TSTLAWGVNL PAHTVIIKGT NVYSPEKGTW
VELSAQDILQ MLGRAGRPRY DKSGEGIIIT SQDEIQYYLA ILNQQLPIES QMMGKLVNSL
NAEVVLGNVK SRDDCVDWLG YTYLFVRMLH SPVLYHVGPE YKDDKLLTEK REDLVHSALT
ILDKNKLIIY DANTGSITST ELGKIASYYY ISYESMNLYN QQLKFFSSPI DILRIFAQSG
EFKYIPVRQE EKMEVSKLLE KAPIPIKEAA ADPLAKINVL LQSYISRLKL DGFALVADMV
YIVQSAGRLL RAIYEIALKK KWSALTRTLL NLSKMVDKRM WLSNSPFRQF PNVPYEIIRK
TENSQMPWSH YFNLSDPAEM SQAIRSEKYG RTAFELLKSF PRLTMAATAQ PITPSLLRVE
LEVLPEWDWN VEIHGYAESF LLLVEDCNGE NILFNDTFLV RKNYINQEHV LEFTVPILEP
LQPNYFISLI SERWLHCEAK IPLRFGRLKV PKKFPAPTQL LNLQLTPVTD LKIKEFENVF
GFEYFNKFQT QAFQSLYNSN ENVLIGMSKG SGKTVCAELS LLNHWKQSKG RAVYISPSQE
KIGYTYKDWK KRFSGIAGGK LVDKLTGELT QDLKILENSH LILSTPQQFD TISRRWKYRK
NIQQIGLFII DDCHTIGNGY AGTVYEVIIS RMRFIHARLE NDLRIVGLTT SLANGKDFAE
WIGVSKNNLF NFSSKERINP LEIRLQSFDI HHNPSLILSM IRPIFQAVAP YSEGESNVTI
FVPSRKHCVE ISAEFVKSAN SHDIDFLKTD LESIEPFLVK ISDAALKESL TNGIGYYYKD
MLPGDKSTVE KLFNAGVLSI LFATRETCFT CPVANFVVVL STQYYEGKEH RYIDYPINEL
LEMIGTSVAD EGGSAKCAIL TNSSKRDYYK KFLNEPLPVE SHLNIFLHDA LINEITTKTV
NSRQDCIDWL TFSYFYRRLQ FNPSFYGVEN TSHLGISEYL SELIENTLKD LVDAKLVEVE
DDEEEEEEEE EENKDDEESE AKVEIVALNG AMIAAYYNIS FISMQTFTLS LTNKTKLKGL
LEIITSASEL EAIPVRKHED EILSKIYNRL PIKSSNPNYE SPFFKSFILL QAHFSRIHLP
HDLVSDQKFI LEKILNLLYA CIDILSSEGY LNAITAMDIS QMIVQAVWDS DPPLKQIPFF
SADILERCAS AKVESVYDIM TLEDDERNNI LKLSDRELSK VAEFVNNYPN VDLSYQLDTS
EPMIANEDRE IIVTLERDEE VDDLTVVAPH YPFKKLENWW VVVGDPKMRQ LYAIKRTTIP
GQSKQIKLDF SIPTAGHHKL SIWCMCDSYV DADKELSFEI DVEESEDAEN KSDANSED
//
