ID A0A1E4TZJ4_PACTA Unreviewed; 126 AA.
AC A0A1E4TZJ4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=13 kDa ribonucleoprotein-associated protein {ECO:0000256|ARBA:ARBA00040411, ECO:0000256|RuleBase:RU366039};
GN ORFNames=PACTADRAFT_55481 {ECO:0000313|EMBL:ODV97157.1};
OS Pachysolen tannophilus NRRL Y-2460.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Pachysolen.
OX NCBI_TaxID=669874 {ECO:0000313|EMBL:ODV97157.1, ECO:0000313|Proteomes:UP000094236};
RN [1] {ECO:0000313|Proteomes:UP000094236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2460 {ECO:0000313|Proteomes:UP000094236};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP
CC particle, required for splicing of pre-mRNA. In association with box
CC C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and
CC site-specific 2'-O-methylation of substrate RNAs. Essential for the
CC accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.
CC {ECO:0000256|ARBA:ARBA00037456, ECO:0000256|RuleBase:RU366039}.
CC -!- SUBUNIT: Component of the U3 snoRNP particle. Binds to the C'/D and B/C
CC motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle,
CC a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA.
CC {ECO:0000256|RuleBase:RU366039}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU366039}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000256|ARBA:ARBA00007337, ECO:0000256|RuleBase:RU366039}.
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DR EMBL; KV454012; ODV97157.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E4TZJ4; -.
DR STRING; 669874.A0A1E4TZJ4; -.
DR OrthoDB; 5481533at2759; -.
DR Proteomes; UP000094236; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd21104; SNU13; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR002415; H/ACA_rnp_Nhp2-like.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004037; Ribosomal_eL8-like_CS.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR InterPro; IPR018492; Ribosomal_eL8/Nhp2.
DR PANTHER; PTHR23105:SF38; NHP2-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR23105; RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00883; NUCLEARHMG.
DR SUPFAM; SSF55315; L30e-like; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366039};
KW Reference proteome {ECO:0000313|Proteomes:UP000094236};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU366039};
KW RNA-binding {ECO:0000256|RuleBase:RU366039};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 19..110
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
SQ SEQUENCE 126 AA; 13629 MW; DF587494143689E7 CRC64;
MSAPNPKAFP LADSALSQQI LDVVQQAQNL RQLKKGANEA TKTLNRGISE FIIMAADTEP
IEILLHLPLL CEDKNVPYVF VPSKTALGRA CGVSRPVIAA SVTTNEASSI KNQIYGIKDK
IETLLI
//
