ID A0A1E4U015_PACTA Unreviewed; 1378 AA.
AC A0A1E4U015;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Ribonuclease II/R domain-containing protein {ECO:0000259|SMART:SM00955};
GN ORFNames=PACTADRAFT_40282 {ECO:0000313|EMBL:ODV97345.1};
OS Pachysolen tannophilus NRRL Y-2460.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Pachysolen.
OX NCBI_TaxID=669874 {ECO:0000313|EMBL:ODV97345.1, ECO:0000313|Proteomes:UP000094236};
RN [1] {ECO:0000313|Proteomes:UP000094236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2460 {ECO:0000313|Proteomes:UP000094236};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV454012; ODV97345.1; -; Genomic_DNA.
DR STRING; 669874.A0A1E4U015; -.
DR OrthoDB; 945235at2759; -.
DR Proteomes; UP000094236; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR Gene3D; 2.40.50.690; -; 1.
DR Gene3D; 2.40.50.700; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR041093; Dis3l2_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR001900; RNase_II/R.
DR PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17877; Dis3l2_C_term; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF00773; RNB; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000094236}.
FT DOMAIN 750..1090
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
FT REGION 101..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1280..1312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 71..99
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 101..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1378 AA; 152939 MW; AABC3F4B0ECB1D1B CRC64;
MSYNNYNNNN NNNQRFNKST NQQDQYLNVP SENLITTTTT TTGGSKPKTL HIAHRRSPSE
LTSLMIEQFN LQRQLEIVQA QQQQILQQQQ QQQQQQQQQQ QAAAALHASS SSLQPPSLPL
SPSHNRNNSS FGSSGSFVPP TSTSPSSSNA HALGHNRRHS LGLNEAKKAA AIVQSQRSSG
KSPTKVSGAS SSEDNSSANS AGTASTNETS ISSMAPPTFK FPPVPVVSST SPSEESTAGG
SGSKGSGVRE PLHMRSRSSA GYSTERSPQR SPQRSFQFPP RQNNGTAVQQ LQPPLPQFSS
HEKRQSGHFR SGSRSSNNEM SMINNNWRNP SHSSSNSSMN GLYNMQNLEA PTASSTFVPS
HRAKSSYGGS ISSLSNFAGN QQQPGQLGSN QRRSLFAPYL PQSSLPDLIN EGRLVTGTLR
VNKKNRSDAY VSTDGLLDAD IFICGSKDRN RALEGDLVAV ELLVVDEVWM SKREKEEKKR
RKDYQQLNGK PSAGDLNDDV HNDASTTYSS SALSAGNSEG SSQGASQQQH SQSLTRKGSL
KQRPTQKKND DVEVEGQSLL LVEEEEISDE YKPLYAGHIV AVVDRIPGQL FSGTLGLLRP
SQASKEKDKN KNSREDDKDA EVMTNSNGKH KRPKIVWFKP TDKKVPLIAI PTEQAPKNFV
EKHEKYANKL FVASIKRWPI TSLHPFGTLI SQLGPMDSAT VEIDAILRDN NFLCDEYPIE
GSAKEETENI KLFNDLPHIQ ESLATEELRR RLFKNEYVIS CTQTNLISDH AFHVKRLTSS
KIELGCHIAD VTYFVKQGSI LDKKAKKRSQ SVFLPQRSTH LLPTKVNNLV SFKENEENLA
ISVIFQIDTT TFEIGDVWIG ESIVVPKQKV DYESIDKILE PDLSTYSNGD NESNGVSNAT
SDYIRTLALI SREFRRQRLE NPALESQPTL PLLDQLDDER VKLTLNIFDP SPSLSMIDEI
FHKVNSAVAQ KIYSKLGDKT LLRRYGIPTL QKLETYHKRI TNLGVSLDTT SSATLQNSVL
SIQDPVKRKC VETLLAKCMG RGKYTIAGKT DPENFPHYLL NLSLYTHFSA PLRRYADLIV
HRQLKAVLND DIEGYTEDTD SLKMTADYCN FKKDCAKSAQ DQAIHLLLSQ TIDDMSEQTG
QLLVMGTVIQ VYESSFDVLI PDFGIEKRVH GDQLPLSKAE FDKKNRVLEL YWEKGVDSAT
FVPEDENDAL SYRASIKNKF RASAVVAATI QNKSAIQNNN INEKLSERLS KFHIKPPKAT
VPAISESPAK LHIQNQVAQS IAASAPTTPR DTTSFNREQL TSSRTVSSSE ILRSSSSGNI
EDGVLRPYLS SCITRVENNY YIQEIRELEQ VPILLRAEIG MALPCLTVRA LNPFYNIK
//
