ID A0A1E4U3N8_PACTA Unreviewed; 611 AA.
AC A0A1E4U3N8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0000259|Pfam:PF00324};
GN ORFNames=PACTADRAFT_184776 {ECO:0000313|EMBL:ODV98607.1};
OS Pachysolen tannophilus NRRL Y-2460.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Pachysolen.
OX NCBI_TaxID=669874 {ECO:0000313|EMBL:ODV98607.1, ECO:0000313|Proteomes:UP000094236};
RN [1] {ECO:0000313|Proteomes:UP000094236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2460 {ECO:0000313|Proteomes:UP000094236};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. YAT (TC 2.A.3.10) family. {ECO:0000256|ARBA:ARBA00006983}.
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DR EMBL; KV454011; ODV98607.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E4U3N8; -.
DR STRING; 669874.A0A1E4U3N8; -.
DR OrthoDB; 1587042at2759; -.
DR Proteomes; UP000094236; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43341; AMINO ACID PERMEASE; 1.
DR PANTHER; PTHR43341:SF15; GENERAL AMINO ACID PERMEASE AGP2; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094236};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..560
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 611 AA; 69063 MW; 78B559F811F3F702 CRC64;
MSKSKLKNFL YDHLVPLPPA KSTTAVLTTT VEQDEKENSQ YVVATGIDRY DKGDYQFRID
TEVDNVASDS SSTLIPSVYT TRRNLKNRHV QLIGIGGTIG TALFVSIGTS LYEGGPLSLL
LSFAIWCIPV FFVTLCTAEM VCFLPTTSPF ITLTGILCDE ALEFMQGFNF WVLQGALIPF
EISGVHTIIE YWNSTHNPGI ELGIQLGLYF IISMSAVSYY GETEFWLSIG KVILAAGLML
FTFFTMVGAN PHRDAYGFRN WNEPSPMVEY LTTGNLGRFQ GFLACLIQAS FTIAGPDYVA
SVAGEIKGEV RKKNLPKAFK QVFFRLTFMF IGGALCVGIV CSSRDSQLIS AISESRPGAG
SSPYVIAMKN LDIPVLPDIV NALLVLSAFS AGNSYTYCTS RTLYGLAKNG KTPKFLTHCT
KNGVPMYCVL ISLCWGLLSL LELGTNSSIV LDWIINLVTQ CQLLNYFLIC STYCFFYKAL
KYKGIDRKDL YFRAWYQPYL AILGAICFFS MIFINPYLLY YPSKEYWSLE TFLFSFLLLF
VDAALYIGYK IIFRTKWRKV SEVNFDKYLK EIEDYEEAYL NSEEYHIDNK DKKQARYWYH
RFLNLIVGDD D
//
