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Database: UniProt
Entry: A0A1E5G7T6_9ENTE
LinkDB: A0A1E5G7T6_9ENTE
Original site: A0A1E5G7T6_9ENTE 
ID   A0A1E5G7T6_9ENTE        Unreviewed;       342 AA.
AC   A0A1E5G7T6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   08-MAY-2019, entry version 12.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=BCR25_12600 {ECO:0000313|EMBL:OEG08768.1};
OS   Enterococcus termitis.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=332950 {ECO:0000313|EMBL:OEG08768.1, ECO:0000313|Proteomes:UP000095094};
RN   [1] {ECO:0000313|EMBL:OEG08768.1, ECO:0000313|Proteomes:UP000095094}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 8895 {ECO:0000313|EMBL:OEG08768.1,
RC   ECO:0000313|Proteomes:UP000095094};
RA   Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OEG08768.1}.
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DR   EMBL; MIJY01000046; OEG08768.1; -; Genomic_DNA.
DR   RefSeq; WP_069665089.1; NZ_MIJY01000046.1.
DR   EnsemblBacteria; OEG08768; OEG08768; BCR25_12600.
DR   PATRIC; fig|332950.4.peg.3686; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000095094; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095094};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       34    334       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   342 AA;  38777 MW;  F0ADE83E1590C10A CRC64;
     MSFKALSQPI DFAQVKSLSK LTTQQAEKKA IRDQELKNII EGKSQKILLL IGPCSAHDED
     AVMEYVTRLA KLQERVQDKV FMVPRVYTNK PRTNGDGYKG LLHQQNPEGE SNLIQGIAAV
     RSLHNRVISE TSLTTADEML YPENLEFVED LVSYIAVGAR SVEDQQHRFV ASGIDQPTGM
     KNPTSGNLKV LFNSLYAAQQ KQEFIFNGME VESSANPLAH VVLRGGLNEY GENLPNYHYE
     DLLKVVEHYK SGQYKNPFIV IDTNHDNSGK QYKEQVRIVK ETLINRSWND DMKQWVRGFM
     IESFLENGRQ EANGKVFGQS ITDPCLGWAE TERLVEYIAE NS
//
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