ID A0A1E5KUK2_9ENTE Unreviewed; 463 AA.
AC A0A1E5KUK2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=L-cystine uptake protein TcyP {ECO:0000256|ARBA:ARBA00022031};
DE AltName: Full=Transporter of cystine TcyP {ECO:0000256|ARBA:ARBA00031293};
GN ORFNames=BCR26_16430 {ECO:0000313|EMBL:OEH81585.1};
OS Enterococcus rivorum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=762845 {ECO:0000313|EMBL:OEH81585.1, ECO:0000313|Proteomes:UP000095256};
RN [1] {ECO:0000313|EMBL:OEH81585.1, ECO:0000313|Proteomes:UP000095256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 25899 {ECO:0000313|EMBL:OEH81585.1,
RC ECO:0000313|Proteomes:UP000095256};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEH81585.1}.
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DR EMBL; MIEK01000043; OEH81585.1; -; Genomic_DNA.
DR RefSeq; WP_069699457.1; NZ_MIEK01000043.1.
DR AlphaFoldDB; A0A1E5KUK2; -.
DR STRING; 762845.BCR26_16430; -.
DR OrthoDB; 7778689at2; -.
DR Proteomes; UP000095256; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF5; L-CYSTINE TRANSPORTER TCYP; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095256};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..21
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 463 AA; 48872 MW; B071D403353F8A7B CRC64;
MTTLITVLVV LTFIGLLYGF YKMQAKHLKF STRVFSALAV GIVFGAIIQF IFGTKNSVTT
QSLEWINIVG NGYVAFLQML VIPLVFVSIV GAFTKMTASK KIGKISFTVL ATLLGTTAIA
ALIGIGTTLL FGLQGAKFTE GTAETARIAE LATRQETVES LSIPEQITAF IPKNVFADFA
GTRPTSTIGV VIFAAFVGIA YLGIKRKSPK EAEFFANLID SLYKITMRIV TLVLRLTPYG
VLALMTNVVA SSDFNAILNL GKFVVASYAA LLAILIVHLL ILITIKVNPI KYLKKAFPVL
SFAFTSRSSA GALPLNIETQ TKALGVDDAT ANFAASFGLS IGQNGCAGVY PAMLATIVAP
TVGINVFSLE FILMLVAIVT ISSFGVAGVG GGATFASLIV LGAMNLPVAI VGLVISVEPL
IDMARTAINV SDTMVAGLVT SAKINELDLD VLNDQSRVVE AEA
//
