ID A0A1E5KZV3_9ENTE Unreviewed; 281 AA.
AC A0A1E5KZV3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=50S rRNA methyltransferase {ECO:0000313|EMBL:OEH83344.1};
GN ORFNames=BCR26_09800 {ECO:0000313|EMBL:OEH83344.1};
OS Enterococcus rivorum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=762845 {ECO:0000313|EMBL:OEH83344.1, ECO:0000313|Proteomes:UP000095256};
RN [1] {ECO:0000313|EMBL:OEH83344.1, ECO:0000313|Proteomes:UP000095256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 25899 {ECO:0000313|EMBL:OEH83344.1,
RC ECO:0000313|Proteomes:UP000095256};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEH83344.1}.
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DR EMBL; MIEK01000008; OEH83344.1; -; Genomic_DNA.
DR RefSeq; WP_069697639.1; NZ_MIEK01000008.1.
DR AlphaFoldDB; A0A1E5KZV3; -.
DR STRING; 762845.BCR26_09800; -.
DR OrthoDB; 5522265at2; -.
DR Proteomes; UP000095256; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR048647; RlmA_N.
DR InterPro; IPR016718; rRNA_m1G-MeTrfase_A_prd.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43460:SF1; METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43460; METHYLTRANSFERASE; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR Pfam; PF21302; RlmA_N; 1.
DR PIRSF; PIRSF018249; MyrA_prd; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR018249-1};
KW Methyltransferase {ECO:0000313|EMBL:OEH83344.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095256};
KW S-adenosyl-L-methionine {ECO:0000256|PIRSR:PIRSR018249-2};
KW Transferase {ECO:0000313|EMBL:OEH83344.1};
KW Zinc {ECO:0000256|PIRSR:PIRSR018249-1}.
FT DOMAIN 20..52
FT /note="23S rRNA (guanine(745)-N(1))-methyltransferase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21302"
FT DOMAIN 97..181
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
FT BINDING 21
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 24
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 37
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 41
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 79
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 103..104
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 190
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
SQ SEQUENCE 281 AA; 32114 MW; CCEEA6BC44DF6CEA CRC64;
MIKKIDSAKA FLENHLEILA CPFCHQPFKL ENFSLVCSQN HQFDLSKKGT LYFLTHSIQT
EYDKKMLFHR GLMIESGMYQ PVLDKLATVI NLEGTTLDVG CGEGSFLSEL SKRGAVGPKI
GFDISKEGIY LASSQPIDAF WCIADLTNLP FSDASIDSVL NIFSPSHYNE FNRVLKPEGA
VVKIVPEVHY LRELREAFYP NNPEKQEYSN EKVVAKFAQE MEMTHNERVT YTFEIPEARR
LDLLEMSPLE WQVDRKVKAE IQANPLTSIT IDVRMLKGNR R
//
