ID   A0A1E5PFI0_9ACTN        Unreviewed;       459 AA.
AC   A0A1E5PFI0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Cytosine or purine or uracil or thiamine or allantoin permease {ECO:0000313|EMBL:OEJ28287.1};
GN   ORFNames=AS594_31200 {ECO:0000313|EMBL:OEJ28287.1};
OS   Streptomyces agglomeratus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=285458 {ECO:0000313|EMBL:OEJ28287.1, ECO:0000313|Proteomes:UP000095759};
RN   [1] {ECO:0000313|EMBL:OEJ28287.1, ECO:0000313|Proteomes:UP000095759}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=6-3-2 {ECO:0000313|EMBL:OEJ28287.1,
RC   ECO:0000313|Proteomes:UP000095759};
RA   Chen X.;
RT   "Complete genome sequence of Streptomyces agglomeratus strain 6-3-2, a
RT   novel anti-MRSA actinomycete isolated from Wuli of Tebit, China.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OEJ28287.1}.
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DR   EMBL; MEHJ01000001; OEJ28287.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E5PFI0; -.
DR   STRING; 285458.BGM19_05535; -.
DR   OrthoDB; 9809167at2; -.
DR   Proteomes; UP000095759; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR   PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR   PANTHER; PTHR31806:SF1; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
DR   PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095759};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002744}.
FT   TRANSMEM        34..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        64..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        396..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        426..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   459 AA;  48297 MW;  99CA73C3779636DE CRC64;
     MADQQQSDEV FHVETHGIDR IPDGERHGSA KDLFWLWFGS NLTFTYVING ALAVAFGLSF
     WQATAVVVVG GLAFFVISAA GLSGIRTGTA TLVISRAAFG TRGNWPAGVL NWIVSIGYTI
     VNTVVGTLAL EVFFAEIGWQ GGDTARALAL LITLTLTFAV AMWGHATVQF AERWMAYALA
     AGFGALLVFV LPGADTTAPA TGPGAAGWSL AFVVMLSSPF SYVPMPADYT RYLPTTTSLR
     SLTCCGALGG FLSSVALGVA GVAAATQTDM TDAVAGTEKL LPGWFQPVFL ALVLLGSVTN
     SIITLYSSSL NLQVLGIPWS RSRAILISAA VTAAGSLWAL FFADFTESLL SFLSLLIIVF
     APWSGVFLTD MVLRRCRYDA DALHAGPGGA YWYRSGYHPA GMAALLTGIA FSALTCDSEL
     WTGPLVAPLG GADLTLLGSV VSALAYWALT ARTPVRSAR
//