ID A0A1E5PUR1_9ACTN Unreviewed; 439 AA.
AC A0A1E5PUR1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:OEJ33230.1};
GN ORFNames=BGK67_19570 {ECO:0000313|EMBL:OEJ33230.1};
OS Streptomyces subrutilus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=36818 {ECO:0000313|EMBL:OEJ33230.1, ECO:0000313|Proteomes:UP000095705};
RN [1] {ECO:0000313|EMBL:OEJ33230.1, ECO:0000313|Proteomes:UP000095705}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10-1-1 {ECO:0000313|EMBL:OEJ33230.1,
RC ECO:0000313|Proteomes:UP000095705};
RA Chen X.;
RT "The complete genome of Streptomyces subrutilus 10-1-1.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ33230.1}.
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DR EMBL; MEHK01000001; OEJ33230.1; -; Genomic_DNA.
DR RefSeq; WP_069921477.1; NZ_MEHK01000001.1.
DR AlphaFoldDB; A0A1E5PUR1; -.
DR STRING; 36818.BGK67_19570; -.
DR OrthoDB; 5242012at2; -.
DR Proteomes; UP000095705; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OEJ33230.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095705};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 38..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..217
FT /note="Putative sensor"
FT /evidence="ECO:0000259|Pfam:PF13796"
FT DOMAIN 245..310
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 351..437
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 439 AA; 46621 MW; 837FC1F713F070A1 CRC64;
MDDGVRAGGG FRAVVRAPVA GRTWREFGHL LIGLPLSVLY FSLAVTGLSL GAGLLVTFLG
VPVLAGVLAM CRGFGHLERA RVRGLLGADV AEPAPIRARK RGAMSAMGAL LQSGSAWRHV
LYSLIHFPWA VFGFCMALVF WTTGWSLLLY PVWFWVFPAY TDQPGLQLFQ NGDYSFYLDS
PAEIALTFLV GLAFTLATPW VFRALTAVDR VVVGGLLGPS RLASRVSELE SDRGVVVDTA
AADLRRIERD LHDGAQARLA ALAMDLGLAK EKATEDPVAA ARMVDEAHGE VKIALQELRD
LARGIHPAVL TDRGLDAALS SVAARCAVPV RVTVDLPARP TAAIEGIAYF TVSELLQNVS
KHARARVAGV EVWKSGERLL VQVSDDGRGG AAMDERPSGA GGTGLAGLAE RLDAVDGILV
VDSPEGAGTT VTAELPWRA
//
