ID   A0A1E5Q1L4_9ACTN        Unreviewed;       572 AA.
AC   A0A1E5Q1L4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Protease {ECO:0000313|EMBL:OEJ35462.1};
GN   ORFNames=BGK67_04105 {ECO:0000313|EMBL:OEJ35462.1};
OS   Streptomyces subrutilus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=36818 {ECO:0000313|EMBL:OEJ35462.1, ECO:0000313|Proteomes:UP000095705};
RN   [1] {ECO:0000313|EMBL:OEJ35462.1, ECO:0000313|Proteomes:UP000095705}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10-1-1 {ECO:0000313|EMBL:OEJ35462.1,
RC   ECO:0000313|Proteomes:UP000095705};
RA   Chen X.;
RT   "The complete genome of Streptomyces subrutilus 10-1-1.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OEJ35462.1}.
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DR   EMBL; MEHK01000001; OEJ35462.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E5Q1L4; -.
DR   STRING; 36818.BGK67_04105; -.
DR   Proteomes; UP000095705; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd07496; Peptidases_S8_13; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR002884; P_dom.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR034176; Peptidases_S8_13.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF01483; P_proprotein; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51829; P_HOMO_B; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000095705};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          452..572
FT                   /note="P/Homo B"
FT                   /evidence="ECO:0000259|PROSITE:PS51829"
FT   ACT_SITE        147
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        208
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        397
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   572 AA;  57152 MW;  03BFD04FD461C7FB CRC64;
     MAVAADVPAS SAAAAATTTA PVENLIVGYK TSASEASSNT AAADDATAKG KKAGKKAKFD
     RRLGTGAALV SLGSATAPAD AAKVMAQFRA DPDVAYVEVD ARAYAMATPN DTEYTKQWDL
     FEPTAGMNVP AAWDKTTGSG VTVAVIDTGY VAHSDLAANV VAGYDFISNA SYARDGGGRD
     GNPADEGDWN ATDNECGLGS KAGGSSWHGT HVAGTIAAAT NNGKGIAGIA YGAKIQPVRV
     LGKCGGTTSD IADAITWASG GTVSGIPANA TPAKVINMSL GGSGACSATY QNAINGAVSR
     GTTVVVAAGN SNSDAAGFTP ASCNNVINVA ASNRTGDRSF YSNYGASIDV AAPGGETRRG
     TDTPGTVTTP ENGILSTLNA GTTTPGAENY KPYQGTSMAA PHVAGLAALA KAAKPSLTPA
     QIEAAIKNNT RPLAGVCTGG CGTGLADAAA TINAVTTTTP TGLENGADYT IGDNTTVESP
     ITVTGKTGNA PATLKVAVNI AHTYIGDLKV DLIAPDGTAY NLHNRTGAGT DNINQTYTVN
     ASAEVANGTW KLRVNDNAGG DTGKIDYWSL TF
//