ID A0A1E5Q5E1_9PROT Unreviewed; 601 AA.
AC A0A1E5Q5E1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=BEN30_14750 {ECO:0000313|EMBL:OEJ65373.1};
OS Magnetovibrio blakemorei.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Magnetovibrionaceae; Magnetovibrio.
OX NCBI_TaxID=28181 {ECO:0000313|EMBL:OEJ65373.1, ECO:0000313|Proteomes:UP000095347};
RN [1] {ECO:0000313|Proteomes:UP000095347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV-1 {ECO:0000313|Proteomes:UP000095347};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ65373.1}.
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DR EMBL; MCGG01000052; OEJ65373.1; -; Genomic_DNA.
DR RefSeq; WP_069958832.1; NZ_MCGG01000052.1.
DR AlphaFoldDB; A0A1E5Q5E1; -.
DR STRING; 28181.BEN30_14750; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000095347; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OEJ65373.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095347}.
FT DOMAIN 23..191
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 212..359
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 527..601
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 601 AA; 66224 MW; E8B57334DEB8D324 CRC64;
MPHQILKDVF GYDSFRPGQF EVVEALLSGE HAMAVMPTGS GKSLCFQIPA LVKGGLTIVV
SPLVALMEDQ VAALKLAGVA AETINSARDR PINVEAWRRV AAGETRLLYL APERLMTERM
LSALTRLPIS LIAIDEAHCM SRWGPSFRPE YEALSKLKDQ FPGVPIAALT ATADTATQED
IAAKLFGGKV KSFVSGFDRP NIRLNVEVRT DPKRQLLDLL KNHEGESGIV YCLSRAKTEK
ITDLLNQNGV RALAYHAGLS ADMRARNQSI FMMEPGVVIV ATIAFGMGID KPDVRFVCHT
DMPGNVEAYY QEIGRAGRDG KPAVAHMFYG LDDLRMRRMF IEQEDSDIDH KRREHKRLDA
LIAYCEAPSC RRQALLAYFE DTIEPCGNCD MCLSPPEMIE GSDTARTLLS ACVNTGQMFG
QAHLIDIVRG ADTEKIRSTG HDQLDAYGRG EDIAKEAWRS IVRQLVAGGF LKIDVTGHGG
LSVTAKGQSL LKGETEFHYR KDLVHKANTK KTRASSGGRA AAPTDLNEED AKLLTQLKDL
RTHLAMEREV PAYMIFSDRS LEDMARQKPR TESSFSDIHG VGAAKLKDFA EAFIGVIVEN
T
//
