ID A0A1E5R150_HANUV Unreviewed; 359 AA.
AC A0A1E5R150;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Transcription factor IWS1 {ECO:0000313|EMBL:OEJ80602.1};
GN ORFNames=AWRI3580_g3990 {ECO:0000313|EMBL:OEJ80602.1};
OS Hanseniaspora uvarum (Yeast) (Kloeckera apiculata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=29833 {ECO:0000313|EMBL:OEJ80602.1, ECO:0000313|Proteomes:UP000095358};
RN [1] {ECO:0000313|Proteomes:UP000095358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI3580 {ECO:0000313|Proteomes:UP000095358};
RX PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT "Genome sequences of three species of Hanseniaspora isolated from
RT spontaneous wine fermentations.";
RL Genome Announc. 4:E01287-E01287(2016).
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ80602.1}.
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DR EMBL; LPNN01000011; OEJ80602.1; -; Genomic_DNA.
DR STRING; 29833.A0A1E5R150; -.
DR VEuPathDB; FungiDB:AWRI3580_g3990; -.
DR OrthoDB; 12240at2759; -.
DR Proteomes; UP000095358; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000095358};
KW Transcription {ECO:0000256|ARBA:ARBA00023015};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 157..242
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 259..299
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 76..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..109
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 41618 MW; 12431B2F2CC5394B CRC64;
MSDIESEKLQ RRQAISDKLD ETIKDMNTKK GSSXRSKKDS IDIDAYTNID SKIQRLKDEM
IQAAKRDNEI ILAQIEGREY NEEESNSKGN EDNEFDLSED EDIEENEDEQ KEQSAAISNA
STVKTIAASK LVLLPKVLHI LNRVDLHESL LENNILLAIR FWLDPLPDGS LPSYEIQKNL
INILIDLNIT NKNENGSFTK YLKESGIGKL LIFYKKSKRV EVNLKRKVER LLSDWSRPII
QASDNYKHKR ILKKEYNYKQ HQIEQTKKLK QNLKRTKEEN ETRKKIKTAQ VNKSQLESER
KMREEGRTVI PVNSVRDYKY APVADLEQLK NLNTELAGVG STLGKNELYK RINKKMGKK
//
