ID A0A1E5R4I0_HANUV Unreviewed; 428 AA.
AC A0A1E5R4I0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Acetylornithine aminotransferase, mitochondrial {ECO:0000256|ARBA:ARBA00021753};
DE EC=2.6.1.11 {ECO:0000256|ARBA:ARBA00012919};
GN ORFNames=AWRI3580_g3927 {ECO:0000313|EMBL:OEJ81781.1};
OS Hanseniaspora uvarum (Yeast) (Kloeckera apiculata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=29833 {ECO:0000313|EMBL:OEJ81781.1, ECO:0000313|Proteomes:UP000095358};
RN [1] {ECO:0000313|Proteomes:UP000095358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI3580 {ECO:0000313|Proteomes:UP000095358};
RX PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT "Genome sequences of three species of Hanseniaspora isolated from
RT spontaneous wine fermentations.";
RL Genome Announc. 4:E01287-E01287(2016).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-
CC L-ornithine from L-glutamate: step 4/4.
CC {ECO:0000256|ARBA:ARBA00005024}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305}.
CC -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC ECO:0000256|RuleBase:RU003560}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ81781.1}.
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DR EMBL; LPNN01000010; OEJ81781.1; -; Genomic_DNA.
DR STRING; 29833.A0A1E5R4I0; -.
DR VEuPathDB; FungiDB:AWRI3580_g3927; -.
DR OrthoDB; 5487467at2759; -.
DR UniPathway; UPA00068; UER00109.
DR Proteomes; UP000095358; Unassembled WGS sequence.
DR GO; GO:0003992; F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00610; OAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004636; AcOrn/SuccOrn_fam.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR00707; argD; 1.
DR PANTHER; PTHR11986:SF79; ACETYLORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR Pfam; PF00202; Aminotran_3; 1.
DR PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aminotransferase {ECO:0000256|ARBA:ARBA00022576,
KW ECO:0000313|EMBL:OEJ81781.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU003560};
KW Reference proteome {ECO:0000313|Proteomes:UP000095358};
KW Transferase {ECO:0000313|EMBL:OEJ81781.1}.
FT UNSURE 188
FT /note="D or N"
FT /evidence="ECO:0000313|EMBL:OEJ81781.1"
FT UNSURE 197
FT /note="D or N"
FT /evidence="ECO:0000313|EMBL:OEJ81781.1"
SQ SEQUENCE 428 AA; 47140 MW; 3C199B56FD4907D2 CRC64;
MLKSLLNKRF NSSSSFKYQV PTYNRPSDII ITSGKGVYLY DSINNKKYLD FTAGIAVTAL
GHNDAQIAKI ISDQVQPGTG LIHSSNLYYN KPSLDLGIKI VXKTVQSGGM HDAKQVFFCN
SGTEANEAAI KFCIKYQETK LNKENIKYRF LALKNSFHGR SLGALAATYN FNYRKPYLSS
LMNVDFIDIA DLSTLKDSIA KAKSNGEVLA GCIVEPIQGE GGINPIPSSL LIELKKTLTS
HDIPLVYDEI QSGVSRSGKL WTHSHYPQEA HPDAITFAKG MGNGVPIGGI IVNDKFTNVI
KAGDHGTTFG GNPLVCAVAN HVIERVTEED FLKNVEKNGE YLQQQLQKKF VDQYSDICVX
VKGKGLMVGL EFKEPPKALV KQCQENGLLV ITAGKSTLRF VPALNIKKEE IDEGLVILEN
AFKKIYQK
//
