ID A0A1E5RA60_9ASCO Unreviewed; 832 AA.
AC A0A1E5RA60;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Phosphopantothenoylcysteine decarboxylase subunit SIS2 {ECO:0000313|EMBL:OEJ83761.1};
GN ORFNames=AWRI3579_g2540 {ECO:0000313|EMBL:OEJ83761.1};
OS Hanseniaspora osmophila.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=56408 {ECO:0000313|EMBL:OEJ83761.1, ECO:0000313|Proteomes:UP000095728};
RN [1] {ECO:0000313|Proteomes:UP000095728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI3579 {ECO:0000313|Proteomes:UP000095728};
RX PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT "Genome sequences of three species of Hanseniaspora isolated from
RT spontaneous wine fermentations.";
RL Genome Announc. 4:E01287-E01287(2016).
CC -!- SIMILARITY: Belongs to the HFCD (homooligomeric flavin containing Cys
CC decarboxylase) superfamily. {ECO:0000256|ARBA:ARBA00038350}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ83761.1}.
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DR EMBL; LPNM01000008; OEJ83761.1; -; Genomic_DNA.
DR STRING; 56408.A0A1E5RA60; -.
DR InParanoid; A0A1E5RA60; -.
DR OrthoDB; 168599at2759; -.
DR Proteomes; UP000095728; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR Gene3D; 3.40.50.1950; Flavin prenyltransferase-like; 1.
DR InterPro; IPR001646; 5peptide_repeat.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR036551; Flavin_trans-like.
DR InterPro; IPR003382; Flavoprotein.
DR PANTHER; PTHR14359; HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY; 1.
DR PANTHER; PTHR14359:SF17; PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE SUBUNIT SIS2-RELATED; 1.
DR Pfam; PF02441; Flavoprotein; 1.
DR Pfam; PF00805; Pentapeptide; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52507; Homo-oligomeric flavin-containing Cys decarboxylases, HFCD; 1.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000095728}.
FT DOMAIN 520..750
FT /note="Flavoprotein"
FT /evidence="ECO:0000259|Pfam:PF02441"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..805
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 89193 MW; CC073F4C6FCAA507 CRC64;
MTTPINTPLG TKAVDLSTDK REGHXDSVGM NENRENREKD YREGSKEQSE DIVSPRFVTS
MSKAEHLHGI VNRATGASAF GANASGANAS GANASGANAS GANASGANAS GANASGASGS
NTSGSNRQLR VTTTATSPTL SEHQREGTRE GAREGQHGLA TPVSILGNAH GSASGFVQPY
TKSIMNVSGS SGAVVSNTPE SGLKRVPTVT FNDLKKQSPL VGHQGISPLP GQQQKDSVRN
ISESTRVQAI DNAMNMASGN NSTNNSTNNS LNNSLGGSQI STPVSAHPLS FSVTSTPKDL
ANTAGGRTNN ITNTSSEAVG YPANTNGNIN NNNNNNNNNN NNKNNNGIGG KGNFFQEHSL
MKSNDVIPEE SISGTRNSSN GSSGSSSYSK NSRNSSIVSL SKQYHDNTNL PVRSSSSSPI
FMTQRKSVHS PILSTNMANG NQNNTNIVSS QNLKSGASNE DLLKKRVGTS PVEISNIIDN
NMNTPLNAQG NHSQPDLNVY GKDTNKNIHP RLQLDDGKFH VLLGACGSMS VLKLKTMIKK
LEDIYGSDKI DIQVILTKSA EMFLNNTPSA NAPPCNVSQI VNSGPSSAQN PGSTNVNPNT
TTTASDPNVQ SPIITYDIPQ HIQVWKDEDE WIVWKQRTDP VLHIELRRWA DILVVAPMTA
NTLSKIALGL CDNLLTNVIR AWNPVSPILL APSMVSNSYN SNVTKRQLKF IKEEMPWIKV
FKPAEKIMGI HGDIGLGGMM DPNEIVNKIV MELGIKDDDD DEEDEDEEED DEEEDDEEED
DEEEEDDDDD DDDEDDDEDD DYDDDEAGAA LHKNDVKGQP DAEQIAQLDQ QE
//
