ID A0A1E5RCA3_9ASCO Unreviewed; 761 AA.
AC A0A1E5RCA3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=AWRI3579_g2501 {ECO:0000313|EMBL:OEJ84223.1};
OS Hanseniaspora osmophila.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=56408 {ECO:0000313|EMBL:OEJ84223.1, ECO:0000313|Proteomes:UP000095728};
RN [1] {ECO:0000313|Proteomes:UP000095728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI3579 {ECO:0000313|Proteomes:UP000095728};
RX PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT "Genome sequences of three species of Hanseniaspora isolated from
RT spontaneous wine fermentations.";
RL Genome Announc. 4:E01287-E01287(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ84223.1}.
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DR EMBL; LPNM01000008; OEJ84223.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E5RCA3; -.
DR STRING; 56408.A0A1E5RCA3; -.
DR InParanoid; A0A1E5RCA3; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000095728; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0022613; P:ribonucleoprotein complex biogenesis; IEA:UniProt.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:OEJ84223.1};
KW Hydrolase {ECO:0000313|EMBL:OEJ84223.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095728}.
FT DOMAIN 103..274
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 299..487
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 761 AA; 85324 MW; 5BC1BB51F85B278A CRC64;
MTPMASDKEI TFSGKGKSPK HHPFKKKIQK TDRVNSPFAR RYPQGNKSTV YFQDALDGED
SIEDEESLGS TFRKSKTDLQ LQSQQLLPGR KALPVYQNKD EIMSYIAQNQ VTVLIGETGS
GKSTQIPQFI MSCLDSNKKK KIAVTQPRRV AAISLATRVA MEYGCNVGDD VGYNVRFDNR
SNDKKTKLKY LTDGMLLREL MLDKNLSQYE YIIIDEAHER TILTDLILGF LKELISPDKN
GARSADLKIV VMSATLQAEK FSEFFNNAPI LFVKGRTYPV ENFYLTTKDS TTQTDVVESM
IRSIVQINSS EPFGGDILCF LPGQEEIDKA VTILSKIAPV LKNSYLSTDV KQKVPELVPL
PLYAALPPNK QLFVFNRLNP KKFQRKVVLS TNIAETSVTI PGVKYVIDSG LRKVKVWRHE
LGLSTLLTVP VSQASCSQRS GRAGREFPGK CYRLFKESDF KKLPPQSEPE IVRCDVANPI
LMLKKIGVDD ILNWSWLENP GKNSIVMGLQ ELYTLNALDD NGKITGKGEK MALLPLAPHL
SNVLLQAIDN NCIEPVLDIV SCLSVENLLL NPLPEKRDEV NEKRFSLCTN GSKYGDLIMM
KELYDMYLSL SSAAEKQNWC QELCVSYRGF KNVLKIKEQL KQYVKKIQGT GASNLSMDDD
NDEMSGASSK TSSLDISSVL KCFLHGFVKN TAIGMPDRSY RTTTTGEVIS VHPSSLLFLN
KTCPAILYTE YVFTTKGYAR NVSRVELQWL QEVALTARKT K
//
