ID   A0A1E5S089_HANUV        Unreviewed;      1122 AA.
AC   A0A1E5S089;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   03-MAY-2023, entry version 28.
DE   SubName: Full=Vacuole morphology and inheritance protein 14 {ECO:0000313|EMBL:OEJ92524.1};
GN   ORFNames=AWRI3580_g123 {ECO:0000313|EMBL:OEJ92524.1};
OS   Hanseniaspora uvarum (Yeast) (Kloeckera apiculata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX   NCBI_TaxID=29833 {ECO:0000313|EMBL:OEJ92524.1, ECO:0000313|Proteomes:UP000095358};
RN   [1] {ECO:0000313|Proteomes:UP000095358}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AWRI3580 {ECO:0000313|Proteomes:UP000095358};
RX   PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA   Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT   "Genome sequences of three species of Hanseniaspora isolated from
RT   spontaneous wine fermentations.";
RL   Genome Announc. 4:E01287-E01287(2016).
CC   -!- SIMILARITY: Belongs to the VAC14 family.
CC       {ECO:0000256|ARBA:ARBA00010225}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OEJ92524.1}.
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DR   EMBL; LPNN01000001; OEJ92524.1; -; Genomic_DNA.
DR   STRING; 29833.A0A1E5S089; -.
DR   VEuPathDB; FungiDB:AWRI3580_g123; -.
DR   OrthoDB; 5481081at2759; -.
DR   Proteomes; UP000095358; Unassembled WGS sequence.
DR   GO; GO:0070772; C:PAS complex; IEA:InterPro.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR026825; Vac14.
DR   InterPro; IPR021841; VAC14_Fig4p-bd.
DR   PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR   PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF12755; Vac14_Fab1_bd; 1.
DR   Pfam; PF11916; Vac14_Fig4_bd; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095358};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          149..184
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   DOMAIN          892..1068
FT                   /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT                   /evidence="ECO:0000259|Pfam:PF11916"
FT   REGION          56..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..88
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..463
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1122 AA;  128421 MW;  73C1CA6ED2C3C5EF CRC64;
     MDPIIIRGLL DRQYEVRKKA ALQLEKQIKF IYYEEQGISR LNKIINQLCG NKKKFFSNES
     KQDDGNDNVD VSANEENHSK KDDKDLDTNS SNNNILSNNT TEAAEIYDNN DIFEGITDIS
     TIRIAKLMAY ASIIISLGQT NSVQFINKII PAMLPFFYDP NDLVRFYSCE SLYNIAKILK
     GEILIYFNEI FDILCSVTVD PINNVRGAAS ILDRLIKDIV IEFGSDYSTL ITLDDDISMT
     TITQNRRTNS SSNKIPDNIR YKDITEQHNL SGKDNNDQPH ILGFDFYQPS NLKLKQPANS
     TIKMEKFVPL LLERIYSNNN NTKVFLMSWI EVLNKCPNLT LVTYLPWLIN AILLYLDDIS
     ESKEITEIAT TLLDGMLKEV TELGTVRTKL CSNEKTSVVS KDITTQKNNI LSNNNQLSEK
     SNSNFMKPHL GKKNYAMSST NKRISSIDSV SSSSSNNNGR YSKVPGGAMT IKDRKKSLII
     NNMSIEDMEE EQEDEIVEAQ VEKDFPQINE NVADGEEYIP RPYLDIKKLI HTLIKSLSSS
     NSQIQKVVLQ WITEIVQYWP ITDILLTRVI KKKNDTDSFE QAETDGKSIE SNDKDLADLI
     SLLLRLGDIN NKSTQQGTKK NAPYETNNLN TSLSDNIGYI DNMVKKPMVS NLLKNNDSSS
     LKNTGTSSVL SNKDILGLTV GNLIENKIIS LAYRLNYKLL EILTISQQIL LQRGMTFNMP
     TTSLINSLAL TFKESCYESR ILILNWLXFV YKYFINTENC EIFNDNCFLI LVKAMSFEED
     XDFYQXVQNN LFNNNXIGST NSSILGKNXF SLYDNLLFDX NENDNDLDKV IKNMDHLNVK
     GNDDNKYLKL XSKSLTLLKM INSLDPNDSY FNKFLNMLLD NWQXQFYDNS PERRETIFVT
     LCVTIGYEKL YKNLSVLLDS RFKSNSNNYK FITEIINMMA KKMIVSKEFY PLRKKLKMND
     DWTFFTILFK SWCIQPSALI YLCLISENYE LGYNIILGFV NLEEILTKNL MQIDILVQLL
     ESQSMTQIRL DLLAPDRQYL IKLLYSILML LPQSSPAFKL LNQRLASVEQ YKNVVSNSFS
     TTSSPIGTAR SSSVNSNKSM MNSNSFQFVD LIDYYHSILN NI
//