ID A0A1E5S181_HANUV Unreviewed; 719 AA.
AC A0A1E5S181;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Ferric reductase transmembrane component 3 {ECO:0000313|EMBL:OEJ92977.1};
GN ORFNames=AWRI3580_g588 {ECO:0000313|EMBL:OEJ92977.1};
OS Hanseniaspora uvarum (Yeast) (Kloeckera apiculata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=29833 {ECO:0000313|EMBL:OEJ92977.1, ECO:0000313|Proteomes:UP000095358};
RN [1] {ECO:0000313|Proteomes:UP000095358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI3580 {ECO:0000313|Proteomes:UP000095358};
RX PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT "Genome sequences of three species of Hanseniaspora isolated from
RT spontaneous wine fermentations.";
RL Genome Announc. 4:E01287-E01287(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ92977.1}.
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DR EMBL; LPNN01000001; OEJ92977.1; -; Genomic_DNA.
DR STRING; 29833.A0A1E5S181; -.
DR VEuPathDB; FungiDB:AWRI3580_g588; -.
DR OrthoDB; 2477110at2759; -.
DR Proteomes; UP000095358; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR PANTHER; PTHR32361:SF9; FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED; 1.
DR PANTHER; PTHR32361; FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000095358};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..719
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009184982"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 280..397
FT /note="Ferric oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01794"
FT DOMAIN 457..543
FT /note="FAD-binding 8"
FT /evidence="ECO:0000259|Pfam:PF08022"
FT UNSURE 460
FT /note="D or N"
FT /evidence="ECO:0000313|EMBL:OEJ92977.1"
SQ SEQUENCE 719 AA; 83043 MW; 8D2EE0A5D624DC59 CRC64;
MLXSTKLFVF LVAAAFNFHV VAAKVSFAKW ETASEISPFY GCKVAVTETA KYCETDDQYI
YGCQCDDVVA FGAMAYCAME NNVNLDHFLK YFNTECNALL VKKYDFTKQD IEDSYKNTSK
YIKTIADFPN FNYTTDILRT PVKTPQLYYS LAYRTYYDYY QNCSWGIIFG AIFLGFWLFY
FVVFGMYQVL FKYIRPTALI NAEFKFKKYN YIMFSKLYNW LDFXKIPIDP NEFNLTKCIG
IGATLIIFFV GSCWNYHSFE GNFFWAKRSS QISRYVGDRT GYLCMFPLNL SIFLAARNNF
LLWCTGWNLA DMIFFHKFFG LLAVVLASAH GIAYWVNAVK TDYYSESYKD DYWIAGVYAI
VIGAAIVILS NHRFVRKHFY EIFLVIHIVL AVVFVIGIWR HLNPLDLVQY IIPFIGIWSL
ERLIRLINMF VVFGGYRKNT ATLYIDESND DKNDIXIKLD INNYNKSLFK IKEGNFGFVY
LGLPFCFWQS HPFTFIKIQD SENFSIVMKV KKGITMKLYK KFLSLGVKTM DLRVCIEGPY
GHSERDFTNK HDQLCVITTG TGIAGPLGYL SSHRASKSFD GQLKPNVLHW GVKSXNIVKT
LENELKTVLS DKNLNIEINI YCKNFVVNSY VEPKKSGTDS LTSSTSXLLA NFKDKFNVVS
GYMNSQNCVD SIFEENNSSL IMTCGLMSVS YQVKKQYMXN VIKNKSTNHI SFIDESQSW
//
