ID A0A1E5UAW2_9FLAO Unreviewed; 601 AA.
AC A0A1E5UAW2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Membrane protein insertase YidC {ECO:0000256|ARBA:ARBA00015325};
DE AltName: Full=Foldase YidC {ECO:0000256|ARBA:ARBA00033342};
DE AltName: Full=Membrane integrase YidC {ECO:0000256|ARBA:ARBA00033245};
GN Name=yidC {ECO:0000313|EMBL:OEL10069.1};
GN ORFNames=BHF72_0763 {ECO:0000313|EMBL:OEL10069.1};
OS Cloacibacterium normanense.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae.
OX NCBI_TaxID=237258 {ECO:0000313|EMBL:OEL10069.1, ECO:0000313|Proteomes:UP000095601};
RN [1] {ECO:0000313|EMBL:OEL10069.1, ECO:0000313|Proteomes:UP000095601}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRS-1 {ECO:0000313|EMBL:OEL10069.1,
RC ECO:0000313|Proteomes:UP000095601};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC {ECO:0000256|ARBA:ARBA00010527}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEL10069.1}.
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DR EMBL; MKGI01000079; OEL10069.1; -; Genomic_DNA.
DR RefSeq; WP_069800555.1; NZ_MKGI01000079.1.
DR AlphaFoldDB; A0A1E5UAW2; -.
DR STRING; 237258.SAMN04489756_10330; -.
DR KEGG; cnr:EB819_09725; -.
DR PATRIC; fig|237258.4.peg.944; -.
DR OrthoDB; 9780552at2; -.
DR Proteomes; UP000095601; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd20070; 5TM_YidC_Alb3; 1.
DR CDD; cd19961; EcYidC-like_peri; 1.
DR Gene3D; 2.70.98.90; -; 1.
DR InterPro; IPR028053; Membr_insert_YidC_N.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR InterPro; IPR047196; YidC_ALB_C.
DR InterPro; IPR038221; YidC_periplasmic_sf.
DR NCBIfam; TIGR03593; yidC_nterm; 1.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF65; INNER MEMBRANE PROTEIN ALBINO3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
DR Pfam; PF14849; YidC_periplas; 1.
DR PRINTS; PR00701; 60KDINNERMP.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000095601};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..324
FT /note="Membrane insertase YidC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14849"
FT DOMAIN 348..545
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
FT REGION 560..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 69140 MW; 3E87655703F39F26 CRC64;
MQKNNGLDKN QLISFVIFSA ILMAFMFYFQ NKQSDEKQVA DAKAKTEQKV ASKTIANNIN
ATVNAAAIKN VTVKNKELTL EFASLGGQLS SVEINQYKAY NAKTDKHDLP LYLIEKNNSS
YGFQFKDKTG KTFNTKDLVF VPSVKDNTVT MTAQVSGATI QYVYQLLDNY TLDFNVKTQG
LSSTVTDEKA DFHWNYTVRG MEKGRSQEQT HSEFNYAFDN YGSTDYDTNG FEEPEETLNW
LAVKQQFFAS IIESTNGFTH AKGTQETIEK GEFLKKFNFD GQVKLAGNEL NQNFKWYFLP
LDLPLLKTFE GKEFDSILPL GWSFIGTLNR IFFVPVYNWL SDWGIAAGWV IFLMTIATKL
ILSPVMFKQH KLSAMMKVVK PEIEEVTEKF KGQENAMKRQ QATMEIYRKA GINQMAGCLP
ALVQIPIFYA LFRFFPNMID LRGKGFWFAN DLTAYDDLIK LPFHIPLIGE HISIFAVACT
IVVLIYTIMT SGQMQQPQQE GMPDMRIIMY IFPITFFFFL NTSSSGLSWY YFVSNALNIL
IILAIKYWIL DEKKIHAQIQ QNKSKAPKPE GKFQKRMREM MEKAQEQQKM QEEQRKKMNK
K
//
