ID A0A1E5X4C2_9PSED Unreviewed; 957 AA.
AC A0A1E5X4C2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:OEO23510.1};
GN ORFNames=AX279_22520 {ECO:0000313|EMBL:OEO23510.1};
OS Pseudomonas sp. J237.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1904754 {ECO:0000313|EMBL:OEO23510.1, ECO:0000313|Proteomes:UP000095383};
RN [1] {ECO:0000313|EMBL:OEO23510.1, ECO:0000313|Proteomes:UP000095383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J237 {ECO:0000313|EMBL:OEO23510.1,
RC ECO:0000313|Proteomes:UP000095383};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEO23510.1}.
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DR EMBL; MKEP01000034; OEO23510.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E5X4C2; -.
DR Proteomes; UP000095383; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR33121:SF23; CYCLIC DI-GMP PHOSPHODIESTERASE PDEB; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13188; PAS_8; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..957
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009189643"
FT TRANSMEM 175..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 401..442
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 552..685
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 696..952
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 957 AA; 107731 MW; 6AFF3DC03140A806 CRC64;
MNLLLSLLLL AFSFAVPAAS LPMQTMTAEQ LVNPVDIKQV LVLEDRNSAL TANEALNQIR
SQGKLVAGTP RLGYSDSAWW VAFELNAPPA MQLEMIIDQA FTDDIELWLY DRDRLIAPIY
SGDHLPFLQR GVPFPRFMLT LPRLGVGPHT LLLRVHSASA VSLPMQLVSS EKNTLLVAVN
WLLGGLLIGG LMSLAVFYML KFRALREQQL GYFCITALAL CAYSASLHGV IDLLFSQWPW
LSKRVVQVAN PLMLIFSTLF IISALRLKLG TVLRLALNVL IAIIVLVSLW NAVYSDDYRG
YQAFNLVLLL VGLFQALVVT LSLIKGLPYS RGYFLCWISA LVMMTVLPLG RLGIINLPSD
AYALQTFLPL LSMLLFSAVL DRQLENVRKA LLSSQSQAID NLEQYRALFN SAREGIFRCT
LNGTLLEANP SLIRFLGSTP GDGSWQALPV QKLLGTTQWT KLVAKLDAAH PSVSQECQLR
DLNGKRHWVY LSLHLRSAHT CIEGIIFDLS DRRQLEDRLK HQAAHDSLTG LLNRRELERL
LQLSLLSNDT SRFSHLLYID LDQFKQVNDL CGHSAGDQLL KQLSAHMQNM LPKSAQLARI
GGDEFVVLMR EQDHFVALGQ AERLRRSVEQ FVFIWENTPF RLHASIGVLT LSQDICDWET
ALRWADSASQ QAKVLGRNRV QQFNPTDGAL QEQQRQLQWI TRLQEAMRSN HFVLFYQPVM
PLQTVHDELH YELLLRYCDP ATGEFISPER FMRAAERYSL LVDIDRWVVR NLCQWLSNNP
EHLQQLGQVN LNLSTHSLLD ASFHIFLSQE LMSKGIPPHK VCIEVTEMVA LGELAVSTKW
LKSLRSQGFK VALDDFGSGF ASYAYLRHLP LDILKIDGSF IRGIEHDRIN QAMVGSMQQI
AKQLGLQTVA EFVETQESLE CLRALGIDYG QGYWIAEPAP LSSLTKPLPT ASARFGL
//
