ID A0A1E7F9U0_9STRA Unreviewed; 471 AA.
AC A0A1E7F9U0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Trypsin-like serine protease {ECO:0000313|EMBL:OEU14941.1};
GN ORFNames=FRACYDRAFT_241501 {ECO:0000313|EMBL:OEU14941.1};
OS Fragilariopsis cylindrus CCMP1102.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC Fragilariopsis.
OX NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU14941.1, ECO:0000313|Proteomes:UP000095751};
RN [1] {ECO:0000313|EMBL:OEU14941.1, ECO:0000313|Proteomes:UP000095751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU14941.1,
RC ECO:0000313|Proteomes:UP000095751};
RG DOE Joint Genome Institute;
RA Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S., Maumus F.,
RA Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R., Veluchamy A.,
RA Ward B.J., Allen A., Barry K., Falciatore A., Ferrante M., Fortunato A.E.,
RA Gloeckner G., Gruber A., Hipkin R., Janech M., Kroth P., Leese F.,
RA Lindquist E., Lyon B.R., Martin J., Mayer C., Parker M., Quesneville H.,
RA Raymond J., Uhlig C., Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C.,
RA Green B., Moulton V., Van Oosterhout C., Grigoriev I.;
RT "Extensive genetic diversity and differential bi-allelic expression allows
RT diatom success in the polar Southern Ocean.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the peptidase S1 family.
CC {ECO:0000256|ARBA:ARBA00007664}.
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DR EMBL; KV784360; OEU14941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7F9U0; -.
DR EnsemblProtists; OEU14941; OEU14941; FRACYDRAFT_241501.
DR KEGG; fcy:FRACYDRAFT_241501; -.
DR InParanoid; A0A1E7F9U0; -.
DR OrthoDB; 2910936at2759; -.
DR Proteomes; UP000095751; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24276:SF91; AT26814P-RELATED; 1.
DR PANTHER; PTHR24276; POLYSERASE-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000313|EMBL:OEU14941.1};
KW Protease {ECO:0000313|EMBL:OEU14941.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095751};
KW Signal {ECO:0000256|SAM:SignalP};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..471
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009192849"
FT DOMAIN 86..358
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT REGION 32..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 52849 MW; EB85C7B43499F38C CRC64;
MATNNNFCHQ HLLLLLVVIV LVIQVVSADD NDSHNTPRQN INNNSSLRHG RRDESSEVEA
EGEADVDEPD QKLKESLLRP EKQTRIINGN QVKELRYPYF ALLTSDQIST EKFRCGAVVI
GPRLVLSVAH CDVFDLDQMS FQIGAYKNLT DGRTVKINSK TIHPQYNETE FLNDIVLYQL
EANMDLPYYI ELDRNSDGKT NGLKKEVVNY DINSSNDEDD KNGTNGNNKL VVIGFGDINP
NDTITELPNS LYKVEVTYVD NKQCDIEHGN NNEITDGMLC AGGDGYDSSF GDSGGPLIKQ
QQQQQQQDTD DDAIDEDAID ADTDDILIGL VSWGRTMNEP GVYVRISYYY TWIRTIVCDQ
YLDDAPDYFE CQTPLPTKEP TNPPRLFDGF KAPTTSKEPP TKVPTKEPTN PPLILDGFIM
NNNDNNNNNT GATETTTTTT KTTEVPTNPY RIPDGFKQSY YNTLISNKSN P
//
