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Database: UniProt
Entry: A0A1E7FFE2_9STRA
LinkDB: A0A1E7FFE2_9STRA
Original site: A0A1E7FFE2_9STRA 
ID   A0A1E7FFE2_9STRA        Unreviewed;       441 AA.
AC   A0A1E7FFE2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   18-SEP-2019, entry version 15.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474};
DE            EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};
GN   ORFNames=FRACYDRAFT_269121 {ECO:0000313|EMBL:OEU16846.1};
OS   Fragilariopsis cylindrus CCMP1102.
OC   Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae;
OC   Bacillariophycidae; Bacillariales; Bacillariaceae; Fragilariopsis.
OX   NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU16846.1};
RN   [1] {ECO:0000313|EMBL:OEU16846.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU16846.1};
RG   DOE Joint Genome Institute;
RA   Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S.,
RA   Maumus F., Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R.,
RA   Veluchamy A., Ward B.J., Allen A., Barry K., Falciatore A.,
RA   Ferrante M., Fortunato A.E., Gloeckner G., Gruber A., Hipkin R.,
RA   Janech M., Kroth P., Leese F., Lindquist E., Lyon B.R., Martin J.,
RA   Mayer C., Parker M., Quesneville H., Raymond J., Uhlig C.,
RA   Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C., Green B.,
RA   Moulton V., Van Oosterhout C., Grigoriev I.;
RT   "Extensive genetic diversity and differential bi-allelic expression
RT   allows diatom success in the polar Southern Ocean.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-
CC         cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-
CC         conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-
CC         ubiquitinyl-L-lysine.; EC=2.3.2.31;
CC         Evidence={ECO:0000256|SAAS:SAAS01116878};
CC   -!- SIMILARITY: Belongs to the RBR family.
CC       {ECO:0000256|SAAS:SAAS00692262}.
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DR   EMBL; KV784358; OEU16846.1; -; Genomic_DNA.
DR   EnsemblProtists; OEU16846; OEU16846; FRACYDRAFT_269121.
DR   KEGG; fcy:FRACYDRAFT_269121; -.
DR   KO; K11968; -.
DR   OrthoDB; 1188714at2759; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR11685; PTHR11685; 1.
DR   Pfam; PF01485; IBR; 1.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00534290};
KW   Repeat {ECO:0000256|SAAS:SAAS01001854};
KW   Transferase {ECO:0000256|SAAS:SAAS01110310};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Ubl conjugation pathway {ECO:0000256|SAAS:SAAS01101469};
KW   Zinc {ECO:0000256|SAAS:SAAS00534327};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175,
KW   ECO:0000256|SAAS:SAAS00534294}.
FT   TRANSMEM    158    176       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    188    208       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    369    393       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26     75       RING-type. {ECO:0000259|PROSITE:PS50089}.
SQ   SEQUENCE   441 AA;  49426 MW;  138B18DCE7153EB3 CRC64;
     MDVVRGMRRS LNHRFKSNLP PSGTACPICF CEPDKHDEWH ITWCGHAICI DCLRQYAANQ
     VKDQEQSGPL KCPVCLKTLR KKDAIVAMTG NSDIIRQWDL KIRNHLLRAI PSFRSCPKCD
     GKDNGGGGGG FVTPECLGVH HQERRDTATR VLQDRNSVLL MVFSIYLVLV GIIATYKSQS
     ASVDLLSMIL PLCVFGKIAL MVQYNLALKA KVQLYRPISV ECPCCDEKFV LPVESEHFQD
     DETSRWMDAN TRPCPSCSVP IAKASGCNHM RCSHCKADFC WACMRLSTSC RAYRCQNGAQ
     YGDATPLFDG GNEQQTLQPD GSIASYIDYI LNNRQCPEVN YCDGVLIFLC LLGRHSSQVQ
     FIANKIMSFL VSVILPLTSI VLGPIVLICF AYTNRQHLQV RLEAPDINQA QEPQRLQANP
     VLELLNQNML TEAIHRSIED Q
//
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