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Database: UniProt
Entry: A0A1E7FFE8_9STRA
LinkDB: A0A1E7FFE8_9STRA
Original site: A0A1E7FFE8_9STRA 
ID   A0A1E7FFE8_9STRA        Unreviewed;       222 AA.
AC   A0A1E7FFE8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   16-JAN-2019, entry version 9.
DE   RecName: Full=Superoxide dismutase {ECO:0000256|RuleBase:RU000414};
DE            EC=1.15.1.1 {ECO:0000256|RuleBase:RU000414};
GN   Name=MnSOD_2 {ECO:0000313|EMBL:OEU16864.1};
GN   ORFNames=FRACYDRAFT_239458 {ECO:0000313|EMBL:OEU16864.1};
OS   Fragilariopsis cylindrus CCMP1102.
OC   Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae;
OC   Bacillariophycidae; Bacillariales; Bacillariaceae; Fragilariopsis.
OX   NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU16864.1};
RN   [1] {ECO:0000313|EMBL:OEU16864.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU16864.1};
RG   DOE Joint Genome Institute;
RA   Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S.,
RA   Maumus F., Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R.,
RA   Veluchamy A., Ward B.J., Allen A., Barry K., Falciatore A.,
RA   Ferrante M., Fortunato A.E., Gloeckner G., Gruber A., Hipkin R.,
RA   Janech M., Kroth P., Leese F., Lindquist E., Lyon B.R., Martin J.,
RA   Mayer C., Parker M., Quesneville H., Raymond J., Uhlig C.,
RA   Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C., Green B.,
RA   Moulton V., Van Oosterhout C., Grigoriev I.;
RT   "Extensive genetic diversity and differential bi-allelic expression
RT   allows diatom success in the polar Southern Ocean.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000414}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC         Evidence={ECO:0000256|RuleBase:RU000414};
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000256|RuleBase:RU000414}.
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DR   EMBL; KV784358; OEU16864.1; -; Genomic_DNA.
DR   KEGG; fcy:FRACYDRAFT_239458; -.
DR   KO; K04564; -.
DR   OrthoDB; 1353361at2759; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000349-1,
KW   ECO:0000256|RuleBase:RU000414};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000414}.
FT   DOMAIN       42    123       Sod_Fe_N. {ECO:0000259|Pfam:PF00081}.
FT   DOMAIN      132    216       Sod_Fe_C. {ECO:0000259|Pfam:PF02777}.
FT   METAL        67     67       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL       115    115       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL       188    188       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
SQ   SEQUENCE   222 AA;  24367 MW;  4B9CE5473B442A39 CRC64;
     MSGGKIILDK ALRSAVNLSS SKLPSEVAKS SAKLFSALSG TKFVLPDLAY DYNALEPAIS
     AETMEIHHSK HHQTYITNLN ATMEKIDSAM IAGDVSGTIA LQGALKFNGG GHINHTLFWE
     NLSPTSTFPT GGPLDKAITD RFGSLDDMIA EMSAKTLAVQ GSGWGWLVYD PKNRRALLIK
     TVLVSMLDMH TRRYRNVDDY LKAIWDIINW DVVEERLIAA SK
//
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