ID A0A1E7FIH7_9STRA Unreviewed; 580 AA.
AC A0A1E7FIH7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=FAD/NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:OEU17989.1};
GN ORFNames=FRACYDRAFT_238420 {ECO:0000313|EMBL:OEU17989.1};
OS Fragilariopsis cylindrus CCMP1102.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC Fragilariopsis.
OX NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU17989.1, ECO:0000313|Proteomes:UP000095751};
RN [1] {ECO:0000313|EMBL:OEU17989.1, ECO:0000313|Proteomes:UP000095751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU17989.1,
RC ECO:0000313|Proteomes:UP000095751};
RG DOE Joint Genome Institute;
RA Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S., Maumus F.,
RA Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R., Veluchamy A.,
RA Ward B.J., Allen A., Barry K., Falciatore A., Ferrante M., Fortunato A.E.,
RA Gloeckner G., Gruber A., Hipkin R., Janech M., Kroth P., Leese F.,
RA Lindquist E., Lyon B.R., Martin J., Mayer C., Parker M., Quesneville H.,
RA Raymond J., Uhlig C., Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C.,
RA Green B., Moulton V., Van Oosterhout C., Grigoriev I.;
RT "Extensive genetic diversity and differential bi-allelic expression allows
RT diatom success in the polar Southern Ocean.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; KV784357; OEU17989.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7FIH7; -.
DR EnsemblProtists; OEU17989; OEU17989; FRACYDRAFT_238420.
DR KEGG; fcy:FRACYDRAFT_238420; -.
DR InParanoid; A0A1E7FIH7; -.
DR OrthoDB; 38914at2759; -.
DR Proteomes; UP000095751; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 2.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 3.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000095751}.
FT DOMAIN 93..165
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 207..293
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 411..563
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
SQ SEQUENCE 580 AA; 64955 MW; AC1E74065289BABB CRC64;
MSTDYDKAES IIDVFDYVIV GTGPSAIGIL LGLLEEISSV LSSKDNTASL SIAIVERGHG
PPHEIATLSP HRWFEAANKS SSTSVRLYPS EIAGKVIEIP VGQGLGGSSN INACLCLPPL
QQDLESWPDP YRSSLVSNAK YLTKIMEKNQ AIHYTSMGNT HNPYSVKNSI LNFRTTVPSL
TTRDAGTKKF VRRNYYDALL DPLMKKHPSL EKNLHWFRGH EAQRLLLKDD STRVIGIECV
STDGDHTSTY REIHARKRVI LCAGAIETPA LLLVSELGHK EHLLGVGQHL MDQAILARIF
FKLPSLKKKI KSPNGVAAIG HLSIVRDHCK RGSQIFQVFI TDPVGDSAAS IISLIIPMAL
RPKWKKKILM NIVEIVLRCV KAILYVTFLY TPAGFLMEQL TTLTMISQMH PRSRGSVKVS
LKNDRVPKMR GPKRRRDVTV EVDPKYLDDP QDRKDLKSGW DTSGRISSSL FETFLSRIFS
VLKFFRTESF WFGLYCRNLL LPYYHYSGTC AMITRTDNND NPNWVVDSSL KVRGHDGLYI
CDASIFPTTI SNPPALTCAA LGYEFARLIF VEDDNKTARR
//
