ID   A0A1E7FJP4_9STRA        Unreviewed;       674 AA.
AC   A0A1E7FJP4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN   ORFNames=FRACYDRAFT_236655 {ECO:0000313|EMBL:OEU18378.1};
OS   Fragilariopsis cylindrus CCMP1102.
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC   Fragilariopsis.
OX   NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU18378.1, ECO:0000313|Proteomes:UP000095751};
RN   [1] {ECO:0000313|EMBL:OEU18378.1, ECO:0000313|Proteomes:UP000095751}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU18378.1,
RC   ECO:0000313|Proteomes:UP000095751};
RG   DOE Joint Genome Institute;
RA   Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S., Maumus F.,
RA   Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R., Veluchamy A.,
RA   Ward B.J., Allen A., Barry K., Falciatore A., Ferrante M., Fortunato A.E.,
RA   Gloeckner G., Gruber A., Hipkin R., Janech M., Kroth P., Leese F.,
RA   Lindquist E., Lyon B.R., Martin J., Mayer C., Parker M., Quesneville H.,
RA   Raymond J., Uhlig C., Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C.,
RA   Green B., Moulton V., Van Oosterhout C., Grigoriev I.;
RT   "Extensive genetic diversity and differential bi-allelic expression allows
RT   diatom success in the polar Southern Ocean.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KV784356; OEU18378.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E7FJP4; -.
DR   EnsemblProtists; OEU18378; OEU18378; FRACYDRAFT_236655.
DR   KEGG; fcy:FRACYDRAFT_236655; -.
DR   InParanoid; A0A1E7FJP4; -.
DR   OrthoDB; 56553at2759; -.
DR   Proteomes; UP000095751; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd20071; SET_SMYD; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46402:SF2; HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5; 1.
DR   PANTHER; PTHR46402; SET AND MYND DOMAIN-CONTAINING PROTEIN 5; 1.
DR   Pfam; PF00856; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095751};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          132..555
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          81..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          560..642
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..380
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        586..603
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   674 AA;  74820 MW;  A51C50F4BA6D5D9F CRC64;
     MPTKQNDPSK DHQISSNIKS LLIAPTLREI AAVLQPSTIH KTFKDMTVTT SSTSSIVVVP
     PVVAELSRSY KYNDHILVKK NDKKTTTRKR PRKDEHADND SSPSRSSSSL QSQSQSQSSP
     LVNNSNTNNC CCCFEVRSCP TKNNQNGIFA TQNIACGDLI IAHEDPIVSS TEQRSSSTFC
     HGCATPIGSL KDHILAAAAA NTAIIGTTTT TTTTTKTKEI LFELPDLPCG LLKNEHGPMF
     SSNNSSSSTL SYRCNIEECG CKKNVVWCST QCRDKTTGNG GNQQQHAFDY VSPTTAVSTT
     EQNNAINNFY KGVTHPMAFQ MAAQSITLIL STILNKFIMK ANQINLNNEN ENEYETTTTK
     TIDNDDDVED LDPLLEHDDD DDDDDLRQYY WWNDYGSHPL WWEVGSKSQS KQRKEQTDTF
     CHLFELHLLK SIKQRRFAAS SSSLLDNENN GGNNVKSNDE ILVQLEKLLK TAVKALCTID
     HIGSILGFDW LADHNVHNSD MNGPVIGSGL YPLLTLANHD CTPNASIEFL QESNRGSMVA
     LRDIVVGEEI CLSYIPSNED EVEEGNDTND SQVTRHFKPT RTEIWLGKQN KITESGSTST
     QQQRQENDDD DDDDGVTVNQ DSPEANHITG SDGDDDDDDD DIILLDDEFS TAKAERARAI
     QEYGFECHCQ RCKQ
//