ID A0A1E7FXP5_9STRA Unreviewed; 793 AA.
AC A0A1E7FXP5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=FRACYDRAFT_177877 {ECO:0000313|EMBL:OEU22906.1};
OS Fragilariopsis cylindrus CCMP1102.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC Fragilariopsis.
OX NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU22906.1, ECO:0000313|Proteomes:UP000095751};
RN [1] {ECO:0000313|EMBL:OEU22906.1, ECO:0000313|Proteomes:UP000095751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU22906.1,
RC ECO:0000313|Proteomes:UP000095751};
RG DOE Joint Genome Institute;
RA Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S., Maumus F.,
RA Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R., Veluchamy A.,
RA Ward B.J., Allen A., Barry K., Falciatore A., Ferrante M., Fortunato A.E.,
RA Gloeckner G., Gruber A., Hipkin R., Janech M., Kroth P., Leese F.,
RA Lindquist E., Lyon B.R., Martin J., Mayer C., Parker M., Quesneville H.,
RA Raymond J., Uhlig C., Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C.,
RA Green B., Moulton V., Van Oosterhout C., Grigoriev I.;
RT "Extensive genetic diversity and differential bi-allelic expression allows
RT diatom success in the polar Southern Ocean.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KV784353; OEU22906.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7FXP5; -.
DR EnsemblProtists; OEU22906; OEU22906; FRACYDRAFT_177877.
DR KEGG; fcy:FRACYDRAFT_177877; -.
DR InParanoid; A0A1E7FXP5; -.
DR OrthoDB; 53793at2759; -.
DR Proteomes; UP000095751; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934:SF237; ATP-DEPENDENT DNA_RNA HELICASE DHX36; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OEU22906.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095751}.
FT DOMAIN 23..187
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 256..429
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 209..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 793 AA; 87340 MW; 2158C95EB6197DE1 CRC64;
MERQRKSLPA WKARDDFLAK LDESCKSGNR VVLVTGDTGC GKTTQIPQFI LEENPTSAKI
VIAQPRRLAA TGVAGRVADE RGEHQAGRAS VGYVVRGDSA FCKDTRLLFC TFGILLRQLQ
SEGALDSITH IVIDEVHERN LDGDILMGLL RKSLKTVPHL KVILMSATLD ADRFAAYWGN
APRLHIPGRT FPVQDFMLED VLELTGYNPP KRKRKQGGFN NYHQQNHGSE TKEEQPQVSL
EDRVKRVDQT SVDYFLLAFL VKYIVQSNQM GSDGSILVFL QGVGEISQAQ KIVESITQGM
SILLLPLHGS LQPQEQSKIF RNTPGQVKVI LSTNVAETSI TIPDCTVVID SCREKQSSYD
PINRMPMLLD QFASKASLKQ RRGRAGRVRS GKCYKLISKA TFSKLNDHTA PEISRCALDQ
TLLSLLFLGA EDGTGRFLQR LLDPPSQASV NAATSSLQKM GALEQAEAGK LRLSPLGMHL
AGIPANPSIG KLLVMGSILG CRTGALAMAA GLSVGRSPFL RVDGRPNRNS EDNGKNQLIL
EERSKLFETC GNSDHSMIAA AFMNWNNLPA GGGRRKRYCE SLGLSFNGMR DIAQLVNQYG
SSLSISGFPS SVESDRNAQS WRVLRTCAIS AMAPDQLVRV YRPSTKYEDT AEGAKLKEGE
ARGHKFYIRR SEERVFIHPS SNMFSVGTYS CPWLVFHSMI RTSKPFLREA TECSAYSLLL
FGGPLTVEAR NSVIHIDGWV RLSANAKIGA LIQGLRSKMD DLLRKKIDNP TISISDTPEM
QLIVKLLVTD GLG
//
