ID A0A1E7FZJ1_9STRA Unreviewed; 440 AA.
AC A0A1E7FZJ1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Diaminopimelate decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=FRACYDRAFT_178499 {ECO:0000313|EMBL:OEU23567.1};
OS Fragilariopsis cylindrus CCMP1102.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Bacillariales; Bacillariaceae;
OC Fragilariopsis.
OX NCBI_TaxID=635003 {ECO:0000313|EMBL:OEU23567.1, ECO:0000313|Proteomes:UP000095751};
RN [1] {ECO:0000313|EMBL:OEU23567.1, ECO:0000313|Proteomes:UP000095751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1102 {ECO:0000313|EMBL:OEU23567.1,
RC ECO:0000313|Proteomes:UP000095751};
RG DOE Joint Genome Institute;
RA Mock T., Otillar R.P., Strauss J., Dupont C., Frickenhaus S., Maumus F.,
RA Mcmullan M., Sanges R., Schmutz J., Toseland A., Valas R., Veluchamy A.,
RA Ward B.J., Allen A., Barry K., Falciatore A., Ferrante M., Fortunato A.E.,
RA Gloeckner G., Gruber A., Hipkin R., Janech M., Kroth P., Leese F.,
RA Lindquist E., Lyon B.R., Martin J., Mayer C., Parker M., Quesneville H.,
RA Raymond J., Uhlig C., Valentin K.U., Worden A.Z., Armbrust E.V., Bowler C.,
RA Green B., Moulton V., Van Oosterhout C., Grigoriev I.;
RT "Extensive genetic diversity and differential bi-allelic expression allows
RT diatom success in the polar Southern Ocean.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|RuleBase:RU003737}.
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DR EMBL; KV784353; OEU23567.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7FZJ1; -.
DR EnsemblProtists; OEU23567; OEU23567; FRACYDRAFT_178499.
DR KEGG; fcy:FRACYDRAFT_178499; -.
DR InParanoid; A0A1E7FZJ1; -.
DR OrthoDB; 317547at2759; -.
DR Proteomes; UP000095751; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:UniProt.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR PANTHER; PTHR43727:SF3; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000095751}.
FT DOMAIN 35..271
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 278..368
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT REGION 418..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 341
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 43
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 440 AA; 49180 MW; E2E24CE3B72AAFF3 CRC64;
MIGPEDTALI FHSWTQHRKY LQHLKQAFTK TDHQNCLHAI AVKTNPHPAI LRQLVEWGFG
LECASMEEVY LAMNAGCPGP NIVFDSPVKT RHEIRICHEN PQLHGILLNV NSLEELDRIP
QNPNFVVGLR INPLVDTGTP EMFQVSGDES KFGTPICSKQ AILDAIRDYP VTQLHVHSGT
AMEDLTVAVG AIASVVDFAT EANTMLLEAG ITDRSIVGVD IGGGLRPEIL ENHESPNPEE
ETSRMEYYVS ELKKAAPALW ENNMKLVTEF GQWSYFYSGY VYSQIEYTLQ REHTRVCYIH
LGADMFLRDI YTGNGRGIEF LPMGAAALRP LTLTDIAGPL CFAGDYLQQQ IQFPKLEEED
EILMLNTGSN AYGLWSRHCS RTVPQVIGVD RDSEILIQMS PRTNPYLSEG YSGTLLPWDA
PEAANNTDDD ENNDDRVASL
//
