ID A0A1E7G8N6_9EURY Unreviewed; 349 AA.
AC A0A1E7G8N6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Heme b synthase {ECO:0000313|EMBL:OEU41338.1};
GN ORFNames=BGV40_15455 {ECO:0000313|EMBL:OEU41338.1};
OS Methanosarcina sp. Ant1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1882735 {ECO:0000313|EMBL:OEU41338.1, ECO:0000313|Proteomes:UP000175834};
RN [1] {ECO:0000313|EMBL:OEU41338.1, ECO:0000313|Proteomes:UP000175834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ant1 {ECO:0000313|EMBL:OEU41338.1};
RA Buongiorno J., Bird J.T., Krivushin K., Oshurkova V., Shcherbakova V.,
RA Rivkina E.M., Lloyd K.G., Vishnivetskaya T.;
RT "Draft Genome Sequence of Antarctic Methanogen Enriched from Dry Valley
RT Permafrost.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEU41338.1}.
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DR EMBL; MDTP02000183; OEU41338.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7G8N6; -.
DR Proteomes; UP000175834; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21123; SPASM_MftC-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR034391; Cmo-like_SPASM_containing.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR030896; rSAM_AhbD_hemeb.
DR NCBIfam; TIGR04545; rSAM_ahbD_hemeb; 1.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR PANTHER; PTHR11228:SF34; TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE COFACTOR MODIFYING PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDF00542; alternative_heme_biosynthesis; 1.
DR SFLD; SFLDG01387; BtrN-like_SPASM_domain_contain; 1.
DR SFLD; SFLDG01072; dehydrogenase_like; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 5..214
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 349 AA; 38741 MW; 9121891E029E8C1C CRC64;
MIAMTNAPRL IAWELTAGCN LNCVHCRGSS TSSVPAGELT TDEAKHFIDE VAGLGKPILI
LSGGEPLIRP DVFEIARYGT DAGFRVVLAT NGTLLTPELV EKLKEAGVQR LSISIDGATA
DTHNEFRGMP GAFERTLAGI EILRKADFPF QINTTISRRN LEEIPKTFEL AKELGAVAYH
VFFLVPTGRG EESDEVSPAD YERILHWFYD MQKESEIQLK ATCAPHYFRI MRQRAKKEGI
EISVKTHGYE AMTKGCLGGT GFCFVSSVGE VYPCGYLPVL AGNIREQSFR DIWENSEVFG
KLRNPEELKG KCGICEYKKV CAGCRARAYA ATGNYLEEEP YCVYRPEKK
//
