ID A0A1E7GD90_9EURY Unreviewed; 607 AA.
AC A0A1E7GD90;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=aldehyde ferredoxin oxidoreductase {ECO:0000256|ARBA:ARBA00012818};
DE EC=1.2.7.5 {ECO:0000256|ARBA:ARBA00012818};
GN ORFNames=BGV40_06720 {ECO:0000313|EMBL:OEU42945.1};
OS Methanosarcina sp. Ant1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1882735 {ECO:0000313|EMBL:OEU42945.1, ECO:0000313|Proteomes:UP000175834};
RN [1] {ECO:0000313|EMBL:OEU42945.1, ECO:0000313|Proteomes:UP000175834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ant1 {ECO:0000313|EMBL:OEU42945.1};
RA Buongiorno J., Bird J.T., Krivushin K., Oshurkova V., Shcherbakova V.,
RA Rivkina E.M., Lloyd K.G., Vishnivetskaya T.;
RT "Draft Genome Sequence of Antarctic Methanogen Enriched from Dry Valley
RT Permafrost.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a
CC carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin];
CC Xref=Rhea:RHEA:16421, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17478,
CC ChEBI:CHEBI:29067, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738; EC=1.2.7.5;
CC Evidence={ECO:0000256|ARBA:ARBA00001714};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the AOR/FOR family.
CC {ECO:0000256|ARBA:ARBA00011032}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEU42945.1}.
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DR EMBL; MDTP02000062; OEU42945.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7GD90; -.
DR Proteomes; UP000175834; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0033726; F:aldehyde ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.569.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2; 1.
DR Gene3D; 1.10.599.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 3; 1.
DR Gene3D; 3.60.9.10; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
DR InterPro; IPR013984; Ald_Fedxn_OxRdtase_dom2.
DR InterPro; IPR013985; Ald_Fedxn_OxRdtase_dom3.
DR InterPro; IPR013983; Ald_Fedxn_OxRdtase_N.
DR InterPro; IPR036503; Ald_Fedxn_OxRdtase_N_sf.
DR InterPro; IPR001203; OxRdtase_Ald_Fedxn_C.
DR InterPro; IPR036021; Tungsten_al_ferr_oxy-like_C.
DR PANTHER; PTHR30038; ALDEHYDE FERREDOXIN OXIDOREDUCTASE; 1.
DR PANTHER; PTHR30038:SF0; TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE; 1.
DR Pfam; PF01314; AFOR_C; 1.
DR Pfam; PF02730; AFOR_N; 1.
DR SMART; SM00790; AFOR_N; 1.
DR SUPFAM; SSF48310; Aldehyde ferredoxin oxidoreductase, C-terminal domains; 1.
DR SUPFAM; SSF56228; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 5..210
FT /note="Aldehyde ferredoxin oxidoreductase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00790"
SQ SEQUENCE 607 AA; 65875 MW; AF6A3BAC0C449C3D CRC64;
MLGGYAGKIL DVNLESGELK DIPLDEAVLR MYLGGKGLGL KLVYNEFRPD MQPFDPDNLL
VFATGPATGG KVPTSGRYHV VCSKSPQTGT VGSGNSGGNW GPYLKFAGYD AVLVRGISKE
PVYLSIVDGK AELVKAPEIW GMTVHAVTDE LTERTGDPKK TSVACIGPAG ENLIPFASIM
NDKYRTAGRT GLGAVMGSKK LKAIVVSGNK RVEPANPELL KERVADSMKK IRENPVTSPT
GGLHTYGTSI LVNIINEHGA YPARNFQEAY FPDADEQSGE TLVKKYLTGR YGCWGCPIIC
GRKSDVPDGP FSVRHTEGPE YETIFAFGSN CGIKELDALV KANHLCDELG LDTISMGDTI
ACAMELVEKG KIPEEKFHGM NLRFGDAGSM IEAIWRTAYR AGFGADLSLG SKKLAEKYGA
PELSITVKGM ELPAYDPRAI EGMGLNYATA NRGGDHVYGY MVSPEILGLP EKLDPYTKEG
KPMWTIILQD LTSAINSSVV CLFTSFALGL PEYAGMLAAI TGFDLDADKL LKLGERVTNL
ERLMNNMYGL DRKEDILPRR LTQEPIPTGP SKGHVSHVPE MIDEYYRLRG WIDGKPTAEK
LKELGIV
//
