ID A0A1E7JRE5_9ACTN Unreviewed; 969 AA.
AC A0A1E7JRE5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
DE Flags: Fragment;
GN ORFNames=AN216_25440 {ECO:0000313|EMBL:OEU90847.1};
OS Streptomyces oceani.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1075402 {ECO:0000313|EMBL:OEU90847.1, ECO:0000313|Proteomes:UP000176101};
RN [1] {ECO:0000313|EMBL:OEU90847.1, ECO:0000313|Proteomes:UP000176101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCSIO 02100 {ECO:0000313|EMBL:OEU90847.1,
RC ECO:0000313|Proteomes:UP000176101};
RX PubMed=27446038; DOI=10.3389/fmicb.2016.00998;
RA Tian X., Zhang Z., Yang T., Chen M., Li J., Chen F., Yang J., Li W.,
RA Zhang B., Zhang Z., Wu J., Zhang C., Long L., Xiao J.;
RT "Comparative Genomics Analysis of Streptomyces Species Reveals Their
RT Adaptation to the Marine Environment and Their Diversity at the Genomic
RT Level.";
RL Front. Microbiol. 7:998-998(2016).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEU90847.1}.
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DR EMBL; LJGU01000160; OEU90847.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7JRE5; -.
DR STRING; 1075402.AN216_25440; -.
DR PATRIC; fig|1075402.3.peg.5563; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000176101; Unassembled WGS sequence.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd08952; KR_1_SDR_x; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 6.10.140.1830; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR041618; PKS_DE.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF18369; PKS_DE; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000176101};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 810..885
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 932..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OEU90847.1"
SQ SEQUENCE 969 AA; 100906 MW; 07AD5DB0A75D1F6D CRC64;
EASEAEVASL LVGRADEVGV AAVNGPSSVV VSGVEAAVTE IGERFRARGA RTRRLSVSHA
FHSPLMEPML AEFRRVAEGV AYGRPSLSVV SNVTGELATV EELTDPEYWV RHVREAVRFA
DGVAALTAQG VTRFVEIGPD GTLTAMARGC VEGEASGGEL SFVPLLRKDR PEVESVLAGV
AGVFVRGQQV DWSAVLPEVP TVPGTDRVDL PTYPFQRERY WLSQRRPDPV TVGHSAELDA
PFWEAVERDD LDSLSGELDI DQDAPWREAL PALASWRQRR RAESEADAWR YRVSWEPYGG
LSGTERVSGR WLVVVPESSG TTESSGTAVP EELLAALGTE PRVVPVPAGA ERADLAERLR
AATASDTEPI DGVVSLLACV EGAGEVGAGG VPVGVVGTLG LVQAMGDVGV GGRLWVLTCG
AVSVGRVEGG PVVGLAGVWG LGRVVGLEWP ELWGGVVDVP GVWDGRVVSR VVGVLGQSVG
AGAGAGAGAG PGAGVEDQVA VRGSGVWVRR VVRAGVAEVG VGGSWVPGSE AGAVLVTGGT
GALGARVARW AVERGARKLV LTSRRGSEAP GAAELERELT ELGAETSVLA CDVTDPEAVA
RLLDQHPVDA VFHAAGVLDD ASVGELAEST LAASWSGKVA GAVHLDALTR DRELSAFVVF
SSIAGVWGSG GQGAYAASNA ALDALVESRR AAGLAGTSVA WGPWAEAGMA ADGAAEEQLR
RRGLSPLPPR EALRALGRVL SAGEGAVVVA DVDWSRFAAA FTSRRAAPLF AELPEAAPAS
ASAPVARTDH DAASELARRL ADASEAERDE AVLTVVRSCA ARALGYAGPK AVESQRAFKD
LGFDSLTAVE LRDQLSGETG VTLPATLVFD HPTPKDLARH VSDQLFSDTV EDSASVIADL
ERIAGAISRF SPDYDARAVI EARLRRMLSE LGESAQGDPQ DQKAAVSQQL DTASDDEIFD
FINQELGRS
//
