ID A0A1E7K0W3_9ACTN Unreviewed; 543 AA.
AC A0A1E7K0W3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=AN217_06510 {ECO:0000313|EMBL:OEU97577.1};
OS Streptomyces qinglanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=943816 {ECO:0000313|EMBL:OEU97577.1, ECO:0000313|Proteomes:UP000175829};
RN [1] {ECO:0000313|EMBL:OEU97577.1, ECO:0000313|Proteomes:UP000175829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCSIO M10379 {ECO:0000313|EMBL:OEU97577.1,
RC ECO:0000313|Proteomes:UP000175829};
RX PubMed=27446038; DOI=10.3389/fmicb.2016.00998;
RA Tian X., Zhang Z., Yang T., Chen M., Li J., Chen F., Yang J., Li W.,
RA Zhang B., Zhang Z., Wu J., Zhang C., Long L., Xiao J.;
RT "Comparative Genomics Analysis of Streptomyces Species Reveals Their
RT Adaptation to the Marine Environment and Their Diversity at the Genomic
RT Level.";
RL Front. Microbiol. 7:998-998(2016).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEU97577.1}.
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DR EMBL; LJGV01000022; OEU97577.1; -; Genomic_DNA.
DR RefSeq; WP_019357548.1; NZ_LJGV01000022.1.
DR AlphaFoldDB; A0A1E7K0W3; -.
DR PATRIC; fig|943816.4.peg.668; -.
DR Proteomes; UP000175829; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000175829}.
FT DOMAIN 9..143
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 146..495
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 320
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 543 AA; 59919 MW; F2A7337CA069CA69 CRC64;
MSATGWAGLV PRAREVRQDD GPPFVWGSGT ALVAGPGARG AARWLRGLAA LPWCEGAGTP
EAPGTQEHPE HPENTVELRI DPGRAPESYL LHVTADRVLV AGGDAAGVFR GVQTLRQLLP
PAAFRRAATA GSWEVPAGAA EDAPRFGWRG LLLDTARHFV PKDGVLRTLD LLALHKLNVL
HLHLTDDQGW RMEIRRHPRL TEVGGWRSRT RVGHRASPLW DERPHGGHYT QDDLREIVAY
AAERHITVVP EIELPGHSQA AIAAYPELGS ADGGAQVWTD WGVSPHLLAP TDEVLRFYEE
VLEEVLEVFP SPFVHIGGDE TPKDQWRESA VAQERIAREG LRDEDALQAW MVRHFDRWLA
ARGRRMTGWD EILQGGTLRD GLTPGAVVSS WRGYEGGVAA ARAGHDVVMC PEHELYLDRR
QAPGEDEPVP LGYVSTLRDV YEMQPVPAEL EREGHAERVL GVQANMWTEC AESVQRLDYQ
MFPRLAAVAE LAWSGPGHAW DDFAARLAEA HLARLDACGV DYRPAAGPRP WQRRPGIPGR
PLE
//
