ID A0A1E7K842_9ACTN Unreviewed; 345 AA.
AC A0A1E7K842;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Adenosine deaminase {ECO:0000313|EMBL:OEV00110.1};
GN ORFNames=AN217_22440 {ECO:0000313|EMBL:OEV00110.1};
OS Streptomyces qinglanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=943816 {ECO:0000313|EMBL:OEV00110.1, ECO:0000313|Proteomes:UP000175829};
RN [1] {ECO:0000313|EMBL:OEV00110.1, ECO:0000313|Proteomes:UP000175829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCSIO M10379 {ECO:0000313|EMBL:OEV00110.1,
RC ECO:0000313|Proteomes:UP000175829};
RX PubMed=27446038; DOI=10.3389/fmicb.2016.00998;
RA Tian X., Zhang Z., Yang T., Chen M., Li J., Chen F., Yang J., Li W.,
RA Zhang B., Zhang Z., Wu J., Zhang C., Long L., Xiao J.;
RT "Comparative Genomics Analysis of Streptomyces Species Reveals Their
RT Adaptation to the Marine Environment and Their Diversity at the Genomic
RT Level.";
RL Front. Microbiol. 7:998-998(2016).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEV00110.1}.
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DR EMBL; LJGV01000022; OEV00110.1; -; Genomic_DNA.
DR RefSeq; WP_069992703.1; NZ_LJGV01000022.1.
DR AlphaFoldDB; A0A1E7K842; -.
DR PATRIC; fig|943816.4.peg.4036; -.
DR Proteomes; UP000175829; Unassembled WGS sequence.
DR GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01430; aden_deam; 1.
DR PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000175829}.
FT DOMAIN 15..336
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
SQ SEQUENCE 345 AA; 36860 MW; 2937C5733BC39F27 CRC64;
MSESSDLAAF IAGLPKAELH VHHVGSASPR IVAELAARHP EAGVPADPEA LADYFTFTDF
AHFIQVYLSV VDLVRDAEDV RLLTYEIARD MARQSIRYAE LTVTPYSSVS RGIPDGAFLE
AIEDARRSAE RELGVVLRWT FDIPGEAGLE AAEETTRIAT ALAPDGLVSF GLGGPEIGVP
RPQFKPYFDR ALATGLHSVP HAGETTGPGT IWDALTSLRA ERIGHGTSAV QDPRLLEHLA
ERGIPLEVCP TSNIATRAVE SLADHPVAEM VKAGVLVTIN SDDPPMFGTD LNTEYGIAAK
LLGLDAAGVA ALARNAVRVS FLDEGGKARL CEEIDAHLAA WQRTG
//
