ID A0A1E7K9P6_9ACTN Unreviewed; 546 AA.
AC A0A1E7K9P6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Beta-N-acetylglucosaminidase {ECO:0000313|EMBL:OEV00649.1};
GN ORFNames=AN217_25835 {ECO:0000313|EMBL:OEV00649.1};
OS Streptomyces qinglanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=943816 {ECO:0000313|EMBL:OEV00649.1, ECO:0000313|Proteomes:UP000175829};
RN [1] {ECO:0000313|EMBL:OEV00649.1, ECO:0000313|Proteomes:UP000175829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCSIO M10379 {ECO:0000313|EMBL:OEV00649.1,
RC ECO:0000313|Proteomes:UP000175829};
RX PubMed=27446038; DOI=10.3389/fmicb.2016.00998;
RA Tian X., Zhang Z., Yang T., Chen M., Li J., Chen F., Yang J., Li W.,
RA Zhang B., Zhang Z., Wu J., Zhang C., Long L., Xiao J.;
RT "Comparative Genomics Analysis of Streptomyces Species Reveals Their
RT Adaptation to the Marine Environment and Their Diversity at the Genomic
RT Level.";
RL Front. Microbiol. 7:998-998(2016).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEV00649.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LJGV01000022; OEV00649.1; -; Genomic_DNA.
DR RefSeq; WP_026004849.1; NZ_LJGV01000022.1.
DR AlphaFoldDB; A0A1E7K9P6; -.
DR PATRIC; fig|943816.4.peg.4754; -.
DR Proteomes; UP000175829; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06564; GH20_DspB_LnbB-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR43678:SF1; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR PANTHER; PTHR43678; PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000175829};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..39
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 40..546
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009196324"
FT DOMAIN 70..194
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 200..527
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 37..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 343
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 546 AA; 59313 MW; 2BDDCE9090711885 CRC64;
MGRNWSKKSG RTAMGALRRS GAPLALTLAV SLLGLTACGG DGDGGGDSPS ASGSGSAQPP
KGPDRLGPAP SAVPSVRQWQ AVRGPGWQRT DRTRVVPAAD SLRDEAKLLA DELKVPVAKA
PSRTGDIELK RGEDGGKSPG GKVNGGPESY RLVSKDGKVT ITGGGDAGVF YGTRTLLQTW
RAQGRFAEGT VADAPDRPQR GFSLDIARKN FSADWIKARI RQMGDLKLNQ LQLHLSDDQA
FRIESETHPE IVSDPHLTKA QVRDIVDLAA SRHITVIPEI DSPGHLGAVL KAHPDLQLRS
ASGATPRGAI DISKPAAAKL VDELLVEFAD LFPGKWAHAG GDEYQALMTQ NPEQTYPGLA
KKAREKFGDK ATVQDLATAW LNDRASTLDK QGKIPQVWND GMHRGGVVEP NKPREVAYWT
GRETGEREPS EYLKEGWKVV NLNDEYLYYV LGQPNNFTYP TGRRIYEEWT PAVVRGTEPV
PDKWAGRDRI LGGRFAVWGD LADAQTTGQV ARGIRLPLAA TAQKLWDPQR PERSWDDFVK
LVDKVD
//
