ID   A0A1E7L4I8_9ACTN        Unreviewed;       864 AA.
AC   A0A1E7L4I8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Helicase {ECO:0000313|EMBL:OEV11041.1};
GN   ORFNames=AN218_14695 {ECO:0000313|EMBL:OEV11041.1};
OS   Streptomyces nanshensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=518642 {ECO:0000313|EMBL:OEV11041.1, ECO:0000313|Proteomes:UP000176005};
RN   [1] {ECO:0000313|EMBL:OEV11041.1, ECO:0000313|Proteomes:UP000176005}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCSIO 10429 {ECO:0000313|EMBL:OEV11041.1,
RC   ECO:0000313|Proteomes:UP000176005};
RX   PubMed=27446038; DOI=10.3389/fmicb.2016.00998;
RA   Tian X., Zhang Z., Yang T., Chen M., Li J., Chen F., Yang J., Li W.,
RA   Zhang B., Zhang Z., Wu J., Zhang C., Long L., Xiao J.;
RT   "Comparative Genomics Analysis of Streptomyces Species Reveals Their
RT   Adaptation to the Marine Environment and Their Diversity at the Genomic
RT   Level.";
RL   Front. Microbiol. 7:998-998(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OEV11041.1}.
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DR   EMBL; LJGW01000252; OEV11041.1; -; Genomic_DNA.
DR   RefSeq; WP_070017340.1; NZ_LJGW01000252.1.
DR   AlphaFoldDB; A0A1E7L4I8; -.
DR   PATRIC; fig|518642.10.peg.2196; -.
DR   Proteomes; UP000176005; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 6.10.140.530; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR005114; Helicase_assoc.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF03457; HA; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:OEV11041.1};
KW   Helicase {ECO:0000313|EMBL:OEV11041.1};
KW   Hydrolase {ECO:0000313|EMBL:OEV11041.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:OEV11041.1}.
FT   DOMAIN          27..209
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          298..483
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          484..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..512
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   864 AA;  94068 MW;  1EF9D20EED7F8FBA CRC64;
     MATVQLRRNQ QEALDAVIPA LDIPSTGEIP PDGIRATIIA APGSGKTRIA AEAARRLTPG
     GRVLVLVPTL DLLTRTVQEW RAAGYRGQAV AVCSLKGDSL LGKLGVRATT SAPQLALWAG
     RGQVVMFATY ASLAAQNAVD DLVLEEGEPA PGVLERALRG VYGQRLDPFD LAVVDEAHRT
     SGDAEKAWAA IHDNARLPAV RRLYMTATAR VWEVPSPSGA PGGSQGLEGA VEGRLVASMD
     NEAIYGPKVH EYGMTEAQER GTLARFVVHV LEIRDPEPPE DADPEEMRGR RLAVLQPALL
     KHMDETGVRS LMTFHHRTLE AMAFARALPQ TAAELHAVDP VVYPKRVGAE WLSGQHSADE
     RRAVLDRFAD GLDEDGWKTD VSFLASCRVL GEGVDIRGER GVGGVVFADT RSSAVDIVQN
     IGRALRQEEG EGKLARIVVP VFLAPGEDPQ NMIASSSYRP LVAVLQGLRS YESAIVEHLE
     LRSRPTGSGV PEDVLASDPQ RHDDETSDEA DGKAAGGGEG SGSAEAGLPP LLNFSSPKDP
     GLIAAFVRTR ILRPESDVWL TGYNAFRQWV GEHGHARMPL DATIVLGEGE EAQEYPVGQW
     GSEQRRAHRD GTLRPWRFEL LDELGMVWSV PDARFEQKVA YFRRYYELHG TLAAPKDAVI
     EDFPVGQALA NLRKPHGLGK DEARAAQRRG ELAAIDRDWN PPWPIAWQRH WVKLRQCLDG
     GATLAEIHPG VRVGGDDVGA WLAEQVAAWW TLSDGQRERM AELGVQAPAD AERRTAEAVG
     STIVVSADAS SQERNLAALR QFHGREGHGK VPRKHRETIL VDDGTGHAVE QRVALGVWRS
     NMRTRRHTLP AELEQHLAQL GLFT
//