ID A0A1E7MVX7_KITAU Unreviewed; 837 AA.
AC A0A1E7MVX7; A0A8H9HPH9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=GCM10010502_34220 {ECO:0000313|EMBL:GGU79604.1}, HS99_0014955
GN {ECO:0000313|EMBL:OEV32580.1};
OS Kitasatospora aureofaciens (Streptomyces aureofaciens).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=1894 {ECO:0000313|EMBL:OEV32580.1, ECO:0000313|Proteomes:UP000037395};
RN [1] {ECO:0000313|EMBL:OEV32580.1, ECO:0000313|Proteomes:UP000037395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10762 {ECO:0000313|EMBL:OEV32580.1}, and ATCC 10762 / DSM
RC 40127 / CCM 3239 / JCM 4008 / LMG 5968 / NBRC 12843 / NCIMB 8234 /
RC A-377 {ECO:0000313|Proteomes:UP000037395};
RA Zhang J.E., Yang H., Guo J., Deng Z., Luo H., Luo M., Zhao B.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000037395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10762 / DSM 40127 / CCM 3239 / JCM 4008 / LMG 5968 / NBRC
RC 12843 / NCIMB 8234 / A-377 {ECO:0000313|Proteomes:UP000037395};
RA Gradnigo J.S., Johnson N., Somerville G.A.;
RT "Sequencing, assembly and comparative genomics of S. aureofaciens ATCC
RT 10762.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:OEV32580.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10762 {ECO:0000313|EMBL:OEV32580.1};
RA Gradnigo J.S., Johnson N., Somerville G.A.;
RT "Sequencing, Assembly and Comparative Genomics of S. aureofaciens ATCC
RT 10762.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:GGU79604.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4434 {ECO:0000313|EMBL:GGU79604.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [5] {ECO:0000313|EMBL:GGU79604.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4434 {ECO:0000313|EMBL:GGU79604.1};
RA Sun Q., Ohkuma M.;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEV32580.1}.
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DR EMBL; BMUB01000007; GGU79604.1; -; Genomic_DNA.
DR EMBL; JPRF03000087; OEV32580.1; -; Genomic_DNA.
DR RefSeq; WP_030553336.1; NZ_LBHA01000063.1.
DR AlphaFoldDB; A0A1E7MVX7; -.
DR GeneID; 33984501; -.
DR OrthoDB; 137117at2; -.
DR Proteomes; UP000037395; Unassembled WGS sequence.
DR Proteomes; UP000610124; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR031634; PknG_rubred.
DR InterPro; IPR031636; PknG_TPR.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF16919; PknG_rubred; 1.
DR Pfam; PF16918; PknG_TPR; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OEV32580.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037395};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW ECO:0000313|EMBL:OEV32580.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 228..508
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 33..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 89396 MW; D9072107D5190644 CRC64;
MGEVCVRPDC SGNGRIDADG YCDECGLTPA GTSTVAPAGT TGTTAPPPAG PGSPCPRDCA
GTIDPDGYCD ECGLTPPGPD TGVTQPYVPS ARVSPDSARS GSIRSLSART GSARSMSGRS
RSHRSTRTGS SRSVSVRSTR GSVSAGTRNR LGAGLVTVPT VATADPAQAV LVNPEVPERK
RFCSKCEAPV GREKNGLPGR PDGFCTKCGT PYSFTPKLRR GDLVGGQYEV VGCLAHGGLG
WIYLAVDRRV NDKWVVLKGL LDTGDEDALA AAVAERRFLA EVDHPNIVRI INFAEHPDLR
TGSTDGYIVM EFVGGKSLKD IANDRRTPDG RREPLPVEQA IAYALEALPA LGYLHGRGLV
YCDFKIDNVI QSGDTLKVID MGAVRRFDDD GPIYGTIGYQ APEIATDGPS PASDLYTVAR
TLAVLTFDFQ GYSTTYRDSL PGPEDVEVFA RYESYYRFLV RATDPDPARR FSSAEEMADQ
LTGVLREVLA LQDDRPRPAL STLFGPELRV VDTELVLPST RPGQLRVGTP DPSAAALALP
VPRVDPGDSN AGFLATLLAT DPEEALVALG GAPAVSVESR LRELRALLEL GRHGTAVQKL
AELEQDHPDD WRVVWYRGLV ALVGSADGGE SGLRAAAEAF DAVYDAFPGE AAPKLALAIC
AELLDDDGDA AEFYRLVWTT DHAYLSAAFG LARVRLAEDD RPGAVRVLES VPATSSQYTA
ARIAAVRARL RERAATDPLA VDLAACSAQL TALRLDDRRR EELSVEVLGA ALDWVGAGSA
GAQQGADLVV LGRPAVEREL RFALEQSYRV LARLADRAET RIEMVERANR ARPRTWV
//
