ID A0A1E7MZ37_KITAU Unreviewed; 1314 AA.
AC A0A1E7MZ37; A0A8H9I3A0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Type VII secretion protein EccC {ECO:0000313|EMBL:OEV33689.1};
GN ORFNames=GCM10010502_66270 {ECO:0000313|EMBL:GGV02304.1}, HS99_0038345
GN {ECO:0000313|EMBL:OEV33689.1};
OS Kitasatospora aureofaciens (Streptomyces aureofaciens).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=1894 {ECO:0000313|EMBL:OEV33689.1, ECO:0000313|Proteomes:UP000037395};
RN [1] {ECO:0000313|EMBL:OEV33689.1, ECO:0000313|Proteomes:UP000037395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10762 {ECO:0000313|EMBL:OEV33689.1}, and ATCC 10762 / DSM
RC 40127 / CCM 3239 / JCM 4008 / LMG 5968 / NBRC 12843 / NCIMB 8234 /
RC A-377 {ECO:0000313|Proteomes:UP000037395};
RA Zhang J.E., Yang H., Guo J., Deng Z., Luo H., Luo M., Zhao B.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OEV33689.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10762 {ECO:0000313|EMBL:OEV33689.1};
RA Gradnigo J.S., Johnson N., Somerville G.A.;
RT "Sequencing, Assembly and Comparative Genomics of S. aureofaciens ATCC
RT 10762.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000037395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10762 / DSM 40127 / CCM 3239 / JCM 4008 / LMG 5968 / NBRC
RC 12843 / NCIMB 8234 / A-377 {ECO:0000313|Proteomes:UP000037395};
RA Gradnigo J.S., Johnson N., Somerville G.A.;
RT "Sequencing, assembly and comparative genomics of S. aureofaciens ATCC
RT 10762.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:GGV02304.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4434 {ECO:0000313|EMBL:GGV02304.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [5] {ECO:0000313|EMBL:GGV02304.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4434 {ECO:0000313|EMBL:GGV02304.1};
RA Sun Q., Ohkuma M.;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEV33689.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BMUB01000027; GGV02304.1; -; Genomic_DNA.
DR EMBL; JPRF03000061; OEV33689.1; -; Genomic_DNA.
DR RefSeq; WP_030289907.1; NZ_LBHA01000291.1.
DR GeneID; 33981071; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000037395; Unassembled WGS sequence.
DR Proteomes; UP000610124; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 3.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000037395};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 450..650
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 809..1000
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 915..951
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 1095..1279
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 473..480
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 827..834
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1112..1119
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1314 AA; 142056 MW; 8CF3F1D2F03EEDE0 CRC64;
MGVIMVKRPA RAYPPTVPDE PVELVSPPEL PRQGGEDWLM SILPMLGMGG SAVFFFSPGA
AAPMKIMGGL MIVSTVGMVL AQIVRARKGG STAMADERRD YLKYLQQTRR QVRRTAESQR
GALLFLNPAP DQLWSIVEDG RRLWERRTGD GDFAQIRVGL GPVQLSTPLV APQTAPMDEL
EPLSAAAMHS FLKAHGTLQD LPLAVSLRAF YHITVCGDPD SVYGNVRAMI AQLTTLHSPD
DLLVAVAAAP GAAEEWDWTK WLPHNQHRKE ADGAGSRRLS AHDLGELEYL LQDELSGRQR
FVRDAAPAAD QPHLVVIMDG AGVPHDSVLA GPEGVQGVTV IEVVPGEVDE PSGHLMVTVS
PQELVLRSAS GATYAGKPDL LSLWQSEALA RQLAPYRASA GGDDEPLLSN LDFTDMMNSG
DPGSFDVARS WRPRAQHERM RVPIGVGANG EHVYLDIKEA ALEGMGPHGL CVGATGSGKS
ELLRTLVLAL AMTHSSETLN FVLADFKGGA TFLGMADMPH TSAVITNLEG ELTLVDRMRD
AIEGELHRRQ ELLHRSGNYA NIHEYERARA AGAALDPLPS LVLIIDEFSE LLSAKPDFIE
MFIQIGRIGR SLGVHLLLAS QRLEEGKLRG LDTYLSYRIG LRTFSAAESR AAIGVPDAYH
LPPVPGVGYL KFGEDVMDRF KAAYVSGPYR APGQQRSTGG RRVNAQPVAF TSAFVDLPPE
PVEEEAPQAP EQDDALVDTV LDVFVQRMAG QGPAAHQVWL PPLDEAPSID HLLPPLQVVP
ERGLTAPGYP GGRLRAPIGI VDKPREQKTD ILEVDFSGAA GHGLIVGGPR SGKSTVLRTM
TAAFGLTHTP REVQFYLLDF GAGSFQSLTG LPHVGGVAGR LDVDKVRRMV SEVHGVMNRR
EELFRATGID TIATYRARRA AGQLPDEAFG DVFLMIDGWN TFKQEFEGLE PVIGDIAQRG
LGYGVHLVIT AARYAEVRPA LKDLLQNRVE LKLGDAMESE VDRRVAQNVP PLAGRGITAE
RLHFLGGLPR LDGSSSVEDL QDGVAGLVTA VDGAWTGPRA PQVRMLPAVL DGNSLPKGFE
HPERGLSFGV DEAELAPVFV NFETDPLFIV FGDTESGKSA LLRMLIKQIT ERYTPDQAGI
VVGDYRRALL GTVPQEYLVE YAAAQPSMAA VVDMLRGACA RRLPGPDVTA EQLRNRSWYS
GKDMFVIVDD YELVATSSGN PLAPLAEFLP FARDIGLRVI VARSAGGAGR SMYEPVMQRM
RELGGQGVIL SGNRDEGALL GTVKPQALPP GRGIYVSRRA TNGQMVQTGW LPVQ
//
