ID A0A1E7RIZ8_9GAMM Unreviewed; 799 AA.
AC A0A1E7RIZ8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:OEY99293.1};
GN ORFNames=BIY45_17675 {ECO:0000313|EMBL:OEY99293.1};
OS Stenotrophomonas sp. BIIR7.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Stenotrophomonas.
OX NCBI_TaxID=1904462 {ECO:0000313|EMBL:OEY99293.1, ECO:0000313|Proteomes:UP000175905};
RN [1] {ECO:0000313|EMBL:OEY99293.1, ECO:0000313|Proteomes:UP000175905}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIIR7 {ECO:0000313|EMBL:OEY99293.1,
RC ECO:0000313|Proteomes:UP000175905};
RA Sanchez-Castro I., Ruiz-Fresneda M.A., Bakkali M., Kampfer P., Busse H.J.,
RA Lopez-Fernandez M., Martinez-Rodriguez P., Merroun M.L.;
RT "Stenotrophomonas bentonitica sp. nov., isolated from bentonite
RT formations.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEY99293.1}.
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DR EMBL; MKCZ01000112; OEY99293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E7RIZ8; -.
DR STRING; 1904462.BIY45_17675; -.
DR Proteomes; UP000175905; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000175905};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 537..722
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 799 AA; 84825 MW; 648A317D9E910ADD CRC64;
MSCVSHRSPR IFAAPLPMFG KAAAAALLCG ACGVVFAPVL MPVVAAWCAL CAGVLLWCSW
GRGRWCGALL VGIGWTTVQG IAGLDLQLPA HATSREYTVQ GRVVDLPQHG PRSTQFRFHV
DDVPAQPDSL RGRELALAWY DAAPTRAPAP RLAVQAGARW QFQARLRPPR GLRNPGSFDA
ERHALLQRLA GTGHVRAGRA LGPPMGLPAW RERMAAAIAV QVPGPGARFV QALALGDTRA
LGQRDWDDLR ALGLTHLIAI SGFHVGLVAG FSAALASLIW RAVSMLGLYW PRPLAAALAA
VAGAAMYAAA AGFALPTVRT VLMIAVVALA RCTRRPGSVG QSLALAALAV LLVDPLSLLA
PGFWLSFAGV LWLVWCLPGR DLHWLRTFLA AQGVATLALL PLTVALFGQA SRAGPLVNLL
AIPWWSLVVV PLSLLGTGLE ALCEGAGRWP WRAAAACFEA SWWLFGIVAQ QPWALWWAPV
AGAGAVPAAL FGVFWLLLPR AAGARVPALL LCLPLLWPAR DRPAPGEVEL LVMDVGQGLA
VWVRTHRHRM LYDAGPAAEG GFDAGERIVV PTLHAVGEAG LDRVLLSHGD RDHAGGMPAV
RLHFGTPPLH APAGAVRADL TPCQRGDRWR WDQVDFSVLH PPATMAYAGN ASSCVLRIQT
VHGAVLLTGD IGHAEEARLL AAAPGALRAE VALVAHHGSA GSSSPDWVQA VAPRLAIVSA
GHGNRFGHPR REVVQRWRAA GAEVLGTADS GALRIWLGRD GLQIREQRLF ERRWWDAAER
ARSAAILSAV INTANGPEG
//
